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• IVIM Papers •
Application of introvoxel incoherent motion sequence in the preoperative T-stage of tongue carcinoma
CHEN Chen  HE Zhong-yun  TIAN- Qiang  HOU Jing  YU Xiao-ping 

DOI:10.12015/issn.1674-8034.2017.04.005.


[Abstract] Objective: To investigate intravoxel incoherent motion MR imaging (IVIM--MRI) in the preoperative T-stage of tongue carcinoma.Materials and Methods: According to the T-stage of Head and Neck Neoplasms AJCC (2010 7th), 47 cases of tongue cancer patients were divided into four groups after searching and screening. Both conventional MRI and IVIM sequences were undergone for each patient who was staged. The accuracy of two methods for T staging of tongue cancer was compared with the pathological results. The value of IVIM parameters (pure molecular diffusion coefficient (D), perfusion-related diffusion coefficient (D*), perfusion fraction (f)) were evaluated on tongue cancer preoperative T-stage by using One-Way ANOVA.Results: Estimating of the tumor preoperative T-stage, the accuracy of the IVIM-MRI was 70.2% which was more accurate than routine MRI (48.9%) and that was statistically significant (P<0.05); The differences of D values in the T-stage groups were statistically significant (P<0.05), performanced for the differences of D value both in the T1 phase tongue carcinoma and T3, 4 phase, and the T2 phase tongue carcinoma and T4 phase were statistically meaningful (P<0.05). But the differences of D* and f in the T-stage were not statistically significant (P>0.05).Conclusion: Compared with routine MRI, IVIM-MRI has certain advantage in differentiating T-stage, and D has a certain value in the preoperative T-stage of tongue cancer.
[Keywords] Tongue neoplasms；Intravoxel incoherent motion；Magnetic resonance imaging；Apparent diffusion coefficient

CHEN Chen The Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

HE Zhong-yun* The Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

TIAN- Qiang The Affiliated No.331 Hospital of Zhuzhou, Changsha Medical University, Zhuzhou 412002, China

HOU Jing The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China

YU Xiao-ping The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, China

*Correspondence to: He ZY, E-mail: hezhongyun@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of 2015 Annual Scientific Research Subject Plan Project supported by Health and Family Planning Commission of Hunan Province No. B2015-161
Received  2017-01-09
Accepted  2017-03-24
DOI: 10.12015/issn.1674-8034.2017.04.005
DOI:10.12015/issn.1674-8034.2017.04.005.

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