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• Clinical Article •
The diagnostic value of ADC combined with DWI in the differentiation of the central neurocytoma and ependymoma
MA Li  PEI Ya-ya  SUN Peng-fei 

DOI:10.12015/issn.1674-8034.2017.04.009.


[Abstract] Objective: To compare and analyze imaging features of lateral ventricular central neurocytoma (CNC) and ependymoma, exploring the value of DWI and ADC value in differential diagnosis of them.Materials and Methods: The clinical and imaging data of 11 cases of lateral ventricular CNC and 17 cases of lateral ventricular ependymoma pathologically confirmed were collected. All patients underwent conventional MRI scan, enhanced scan and diffusion weighted MRI scan. The results were analyzed in all cases.Results: Eleven cases of lateral ventricular CNC showed equal or slightly higher signal on DWI, and the ADC mean was (0.65±0.12)×10-3 mm2/s. In 12 from 17 cases of lateral ventricular ependymoma, DWI showed higher or slightly higher signal, 5 cases showed low signal, ADC mean was (1.21±0.24)×10-3 mm2/s, Which was significantly higher than that of CNC (P<0.001). When optimal cut point of ADC was 0.87×10-3 mm2/s for diagnosis of CNC and ependymoma, the area under the ROC curve was 0.98±0.01, 95% confidence intervals was 0.95—1.00, the sensitivity, specificity and accuracy was 90%, 100% and 90%.Conclusion: The imaging features are helpful in differential diagnosis of lateral ventricular CNC and ependymoma, DWI and ADC values can be applied as a complementary tool in the preoperative diagnosis and differential diagnosis of them, which can increase the diagnostic accuracy.
[Keywords] Central neurocytoma；Ependymoma；Apparent diffusion coefficient；Magnetic resonance imaging；Diffusion weighted imaging

MA Li Department of Radiotherapy, the Second Hospital Affiliated to Lanzhou University, Lanzhou 730030, China

PEI Ya-ya Department of Radiotherapy, the Second Hospital Affiliated to Lanzhou University, Lanzhou 730030, China

SUN Peng-fei* Department of Radiotherapy, the Second Hospital Affiliated to Lanzhou University, Lanzhou 730030, China

*Correspondence to: Sun PF, E-mail: sunpengfeiby@163.com

Conflicts of interest   None.

Received  2016-11-28
Accepted  2016-12-25
DOI: 10.12015/issn.1674-8034.2017.04.009
DOI:10.12015/issn.1674-8034.2017.04.009.

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