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• Review •
Research status of ASL perfusion imaging and dynamic contrast-enhanced MRI in the periphery of gliomas
WANG Ya-qin  WANG Qian-qian  DONG Peng 

DOI:10.12015/issn.1674-8034.2017.05.013.


[Abstract] Glioma is a common intracranial primary tumor. Glioma has invasive growth, and it is important to correctly determine the boundary of the tumor to guide surgery and determine the postoperative radiotherapy boundaries. With the development of magnetic resonance perfusion imaging, ASL can be a noninvasive perfusion MR method for evaluation of the MVD of brain gliomas. Dynamic contrastenhanced MRI (DCE-MRI) is a useful way to evaluate the angiogenesis of glioma. In recent years, their furthers in the periphery of gliomas have become a hot spot. In this paper, we made a review from the aspects of DCE-MRI and ASL perfusion imaging in the periphery of gliomas.
[Keywords] Glioma；Neoplasm invasiveness；Magnetic resonance imaging

WANG Ya-qin Imaging Center of affiliated hospital, Weifang Medical University, Weifang 261031, China

WANG Qian-qian Imaging Center of affiliated hospital, Weifang Medical University, Weifang 261031, China

DONG Peng* Imaging Center of affiliated hospital, Weifang Medical University, Weifang 261031, China

*Correspondence to: Dong P, E-mail: dongpeng01502@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This paper is funded by the Province Natural Science Fundation of Shan Dong No. ZR2014HL083
Received  2016-12-21
Accepted  2017-04-01
DOI: 10.12015/issn.1674-8034.2017.05.013
DOI:10.12015/issn.1674-8034.2017.05.013.

[1]
李俊芝, 马遇庆, 张巍, 等. 1629例中枢神经系统肿瘤的临床病理分析. 中国现代医学杂志, 2011, 21(16): 1910-1917.
[2]
车英玉, 杨志涛, 程敬亮. 3D ASL与DSC灌注技术在脑肿瘤的对比研究.临床放射学杂志, 2014, 33(5): 770-773.
[3]
Noguchi T, Yoshiural T, Hiwatashi A, et al. Perfusion neuroimaging using arterial spin-labeling: correlation with histopathologic vascular density. AJNR Am J Neuroradiol, 2008, 29(4): 688-93.
[4]
陈发军, 周东, 黄飚. 脑胶质瘤分级诊断的新方法:动脉自旋标记技术. 中华神经外科疾病研究杂志, 2010, 1(9): 27-30.
[5]
Wolf RL, Wang JJ, Wang SM, et al. Grading of CNS neoplasms usingcontinuous aterial spin labeled perfusion MR imaging at 3 tesla. J Magn Reson Imaging, 2005, 22(4): 475-82.
[6]
朱记超, 娄明武, 张方璟, 等. 动脉自旋标记技术在脑肿瘤术前评估中的应用研究.临床放射学杂志, 2012, 31(12): 1688-1693.
[7]
王利, 郑罡, 赵铁柱, 等. 动脉自旋标记技术在脑部疾病中的临床应用. 生物医学工程杂志, 2013, 30(1):195-199.
[8]
王子文, 杨本强, 刘文源, 等. 胶质瘤3DASL灌注指数与VEGF MVD表达相关性研究. 中国肿瘤临床, 2016, 43(13) : 557-561.
[9]
Ningning D, Haopeng P, Xuefei D, et al. Perfusion imaging of brain gliomas using arterial spin labeling: correlation with histopathological vascular density in MRI-guided biopsies. Neuroradiology, 2017, 59(1): 51-59.
[10]
Brandão LA, Shiroishi MS, Law M. Brain tumors: a multimodality approach with diffusion-weighted imaging, diffusion tensor imaging, magnetic resonance spectroscopy, dynamic susceptibility contrast and dynamic contrast enhanced magnetic resonance imaging. Magn Reson Imaging Clin N Am, 2013, 21(2): 199-239.
[11]
廖海波, 肖新兰, 戴中强, 等. 3.0 T MR3D-PCASL技术在脑胶质瘤微灌注研究. 实用放射学杂志, 2016, 32(3): 441-451.
[12]
Lin L, Xue Y, Duan Q, et al. The role of cerebral blood flow gradient in peritumoral edema for differentiation of glioblastomas from solitary metastatic lesions. Oncotarget, 2016, 7(42): 69051-69059.
[13]
张清波. MR灌注成像对大鼠脑C6胶质瘤血管生成的实验研究. 复旦大学, 2006.
[14]
彭靖, 戴建平, 朱明旺, 等. MR脑血流灌注成像在星形细胞肿瘤中的应用研究. 中华放射学杂志, 2003, 37(7): 636-639.
[15]
丁芳芳. 高级别星形细胞肿瘤ASL灌注成像的初步研究. 河北医科大学, 2014.
[16]
Halshtok NO, Sadetzki S, Chetrit A, et al. Perfusion-weighted imaging of peritumoral edema can aid in the differential diagnosis of glioblastoma mulltiforme versus brain metastasis. Isr Med Assoc J, 2013, 15(2):103-105.
[17]
王文娟, 徐敏, 孙永红, 等. 正常大鼠部分脑组织切除术后术区周边脑组织MRI增强特点及其病理学研究. 实用放射学杂志, 2014, 30(12): 2076-2078, 2093.
[18]
Cha S, Johnson G, Wadghiri YZ, et al. Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology. Magn Reson Med, 2003, 49(5): 848-55.
[19]
姜新雅, 王小宜, 陈宇, 等. 髓外硬膜下肿瘤的常规和动态增强MRI研究. 中国医学影像技术, 1999, 15 (1): 23-25.
[20]
Tofts PS, Brix G, Buckley DL, et al. Estimating kinetic parameters from dynamic contrast-enhanced T1-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging, 1999, 10(3): 223-232.
[21]
Wang XF, Lin GS, Lin ZX, et al. Association of pSTAT3-VEGF signaling pathway with peritumoral edema in newly diagnosed glioblastoma: an immunohistochemical study. Int J Clin Exp Pathol, 2014, 7(9): 6133-40.
[22]
Engelhorn T, Savaskan NE, Schwarz MA, et al. Cellular characterization of the peritumoral edema zone in malignant brain tumors. Cancer Sci, 2009, 100(10): 1856-1862.
[23]
Nägele T, Petersen D, Klose U, et al. Dynamic contrast enhancement of intracranial tumors with snapshot-FLASH MR imaging. AJNR Am J Neuroradiol, 1993, 14(1): 89-98.
[24]
陈杰云, 林晓莹, 陈向荣, 等. MR灌注加权成像鉴别诊断单发脑转移瘤与高级别胶质瘤. 中国医学影像技术, 2015, 31(2): 215-217.
[25]
Knopp EA, Cha S, Johnson G, et al. Glial neoplasms:dynamic contrast-enhanced T2*-weighted MR imaging. Radiology, 1999, 211(3):791-798.
[26]
Lehmann P, Vallée JN, Saliou G, et al. Dynamic contrast-enhancedT2*-weighted MR imaging: a peritumoral brain oedema study. J Neuroradiol, 2009, 36(2): 88-92.
[27]
丁爽, 贾文霄, 许永华, 等. DCE_MRI联合DWI评价肿瘤血管生成的实验研究. 中国医学计算机成像杂志, 2012,18(6): 542-547.
[28]
宋媛, 丁爽, 贾文霄. DCE-MRI评价肿瘤血管生成的实验研究. 放射学实践, 2014, 29(6): 640-643.
[29]
贾龙威, 牛蕾, 马文帅, 等. 血流动力学双室模型Extende Tofts Linear在脑胶质瘤DCE-MRI渗透性定量分析的复测性及有效性研究. 磁共振成像, 2015, 6(8): 571-574.
[30]
黄杰, 李晓光, 康厚艺, 等. DSC-MRI和DCE-MRI定量分析在脑胶质瘤分级诊断中的应用. 第三军医大学学报, 2015, 37(7): 672-677.
[31]
李锐, 刘晋红, 王玉林, 等. 三维动脉自旋标记与磁共振动态对比增强成像参数在胶质瘤术前分级中的对照研究. 肿瘤影像学, 2016, 25(3): 217-222.
[32]
张微, 牛蕾, 马敏阁, 等. DCE-MRI在高、低级别脑胶质瘤及脑膜瘤中的鉴别诊断. 磁共振成像, 2015, 6(8): 566-570.
[33]
王俊丽, 范淼, 初建平, 等. DCE-MRI和DWI在界定儿童脑胶质瘤边界中的诊断价值. 中山大学学报, 2016, 37(1): 155-160
[34]
关丽明, 郭敏, 徐克, 等. 大鼠C6脑胶质瘤生长的MRI评价及与其病理组织学的关系. 中国医学影像学杂志, 2006, 14(3): 201-204.
[35]
印弘, 李复, 高元桂, 等. 大鼠C6胶质瘤VEGF表达与MRI对照研究. 中国医学影像学杂志, 2002, 10(3): 200-202.
[36]
杜学松, 刘恒, 陈晓, 等. 动态对比增强MRI评价大鼠C6胶质瘤肿瘤边缘新生血管的实验研究. 中国医学影像学, 2015, 23(2), 81-86.
[37]
Xuesong D, Wei X, Heng L, et al. Evaluation of neovascularization patterns in an orthotopic rat glioma model with dynamic contrastenhanced MRI. Acta Radiol, 2016, 30(6): 1-9.
[38]
Warmuth C, Gunther M, Zimmer C. Quantification of blood flow in brain tumors: comparison of arterial spin labeling and dynamic susceptibility-weighted contrast-enhanced MR Imaging. Radiology, 2003, 228(2): 523-532.

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