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• Clinical Article •
Preliminary study on myocardial strain in patients with hypertrophic cardiomyopathy by MR feature tracking
TENG Fei  LIU Ting  DAI Xu 

DOI:10.12015/issn.1674-8034.2017.06.006.


[Abstract] Objective: The feature tracking technique of cardiac magnetic resonance (CMR-FT) was used to analyze the cardiac function and myocardial segmental strain in patients with hypertrophic cardiomyopathy (HCM), and to explore the feasibility of CMR-FT in the detection of early deformation abnormalities in patients with hypertrophic cardiomyopathy.Materials and Methods: 17 hypertrophic cardiomyopathy patients and 14 healthy subjects as control cases were enrolled in our study. CMR was performed on 3.0 T scanner with the sequence of cine steadystate free precession. Cardiac functional segmental strain (38 segments of HCM and 38 segments of healthy subjects) was measured using CVI software.Results: Left ventricular function parameters (left ventricular end-diastolic volume, left ventricular end-systolic volume and left ventricular ejection fraction) had no difference between HCM patients and healthy subjects (all P>0.05). Segmental strain were significantly lower in patients with HCM compared to healthy subjects (all P<0.05): circumferential strain[(-5.26±2.70)% vs (-11.68±2.06)%], longaxis strain [(-7.92±5.07)% vs (-13.93±3.89)%] and peak systolic circumferential strain[(-10.44±5.46)% vs (-18.43±2.99)%], peak systolic longitudinal strain[(-12.29±8.17)% vs (-20.26±2.93)%].Conclusion: For hypertrophic cardiomyopathy patients with normal cardiac function, CMR-FT can detect changes of strain in hypertrophic myocardial segment in early stage, CMR-FT is able to find myocardial systolic dysfunction earlier than left ventricular function parameters.
[Keywords] Magnetic resonance imaging；Cardiovascular magnetic resonance；Feature tracking；Cardiomyopathy, hypertrophic

TENG Fei Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

LIU Ting Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

DAI Xu* Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

*Correspondence to: Dai X, E-mail: daixudex@vip.sina.com

Conflicts of interest   None.

Received  2017-02-14
Accepted  2017-03-25
DOI: 10.12015/issn.1674-8034.2017.06.006
DOI:10.12015/issn.1674-8034.2017.06.006.

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