Share：
Share this content in WeChat
X
[Chinese][PDF]80599
• Clinical Article •
Preliminary study on myocardial strain in patients with hypertrophic cardiomyopathy by MR feature tracking
TENG Fei  LIU Ting  DAI Xu 

DOI:10.12015/issn.1674-8034.2017.06.006.


[Abstract] Objective: The feature tracking technique of cardiac magnetic resonance (CMR-FT) was used to analyze the cardiac function and myocardial segmental strain in patients with hypertrophic cardiomyopathy (HCM), and to explore the feasibility of CMR-FT in the detection of early deformation abnormalities in patients with hypertrophic cardiomyopathy.Materials and Methods: 17 hypertrophic cardiomyopathy patients and 14 healthy subjects as control cases were enrolled in our study. CMR was performed on 3.0 T scanner with the sequence of cine steadystate free precession. Cardiac functional segmental strain (38 segments of HCM and 38 segments of healthy subjects) was measured using CVI software.Results: Left ventricular function parameters (left ventricular end-diastolic volume, left ventricular end-systolic volume and left ventricular ejection fraction) had no difference between HCM patients and healthy subjects (all P>0.05). Segmental strain were significantly lower in patients with HCM compared to healthy subjects (all P<0.05): circumferential strain[(-5.26±2.70)% vs (-11.68±2.06)%], longaxis strain [(-7.92±5.07)% vs (-13.93±3.89)%] and peak systolic circumferential strain[(-10.44±5.46)% vs (-18.43±2.99)%], peak systolic longitudinal strain[(-12.29±8.17)% vs (-20.26±2.93)%].Conclusion: For hypertrophic cardiomyopathy patients with normal cardiac function, CMR-FT can detect changes of strain in hypertrophic myocardial segment in early stage, CMR-FT is able to find myocardial systolic dysfunction earlier than left ventricular function parameters.
[Keywords] Magnetic resonance imaging；Cardiovascular magnetic resonance；Feature tracking；Cardiomyopathy, hypertrophic

TENG Fei Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

LIU Ting Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

DAI Xu* Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang 110001, China

*Correspondence to: Dai X, E-mail: daixudex@vip.sina.com

Conflicts of interest   None.

Received  2017-02-14
Accepted  2017-03-25
DOI: 10.12015/issn.1674-8034.2017.06.006
DOI:10.12015/issn.1674-8034.2017.06.006.

[1]
Force M, Elliott PM, Anastasakis A, et al. 2014 ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J, 2014, 35(39): 2733-2779.
[2]
徐念, 梁天山, 郭顺华, 等. 多层螺旋CT与心脏超声心动图检查对肥厚型心肌病诊断的比较分析. 黑龙江医药, 2016, 29(1): 116-118.
[3]
韩勇, 陈明. 超声、CT和MRI测定局部心肌应变的研究进展. 中国医学影像学杂志, 2014, 22(3): 233-236.
[4]
Narous M. Do whole body impedance cardiography estimates of left ventricular structure, volumes and function correlate with the gold standard of cardiac magnetic resonance imaging?. J Cardiovascular Mag Reson, 2016, 18(1): 194.
[5]
罗亚雄, 石翔, 王福军. 肥厚型心肌病的研究进展. 中西医结合心血管病电子杂志, 2016, 4(3):5-8.
[6]
Kawasaki T, Sugihara H. Subendocardial ischemia in hypertrophic cardiomyopathy. J Cardiology, 2014, 63(2): 89-94.
[7]
Moon JC, Reed E, Sheppard MN, et al. The histologic basis of late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy. J American College of Cardiology, 2004, 43(12): 2260-2264.
[8]
Moravsky G, Bruchal-Garbicz B, Jamorski M, et al. Myocardial mechanical remodeling after septal myectomy for severe obstructive hypertrophic cardiomyopathy. J American Society of Echocardiography Official Publication of the American Society of Echocardiography, 2013, 26(8): 893-900.
[9]
Nakano S, Takahashi M, Kimura F, et al. Cardiac magnetic resonance imaging-based myocardial strain study for evaluation of cardiotoxicity in breast cancer patients treated with trastuzumab: a pilot study to evaluate the feasibility of the method. Cardiology J, 2016, 23(3): 270-280.
[10]
Schuster A, Paul M, Bettencourt N, et al. Cardiovascular magnetic resonance myocardial feature tracking for quantitative viability assessment in ischemic cardiomyopathy. Inter J Cardiology, 2013, 166(2): 413-420.
[11]
Bogarapu S, Puchalski MD, Everitt MD, et al. Novel cardiac magnetic resonance feature tracking (CMR-FT) analysis for detection of myocardial fibrosis in pediatric hypertrophic cardiomyopathy. Pediatric Cardiology, 2016, 37(4): 663-673.
[12]
Almaas VM, Haugaa KH, Strøm EH, et al. Noninvasive assessment of myocardial fibrosis in patients with obstructive hypertrophic cardiomyopathy. Heart, 2014, 100(8): 631-638.
[13]
张红菊, 王浩, 杨浣宜, 等. 超声斑点追踪技术评价肥厚型心肌病患者左心室容积及其收缩功能的临床研究. 中国超声医学杂志, 2013, 29(6): 492-495.
[14]
Smith BM, Dorfman AL, Yu S, et al. Relation of strain by feature tracking and clinical outcome in children, adolescents, and young adults with hypertrophic cardiomyopathy. American J Cardiology, 2014, 114(8): 1275-1280.
[15]
Kutty S, Rangamani S, Venkataraman J, et al. Reduced global longitudinal and radial strain with normal left ventricular ejection fraction late after effective repair of aortic coarctation- a CMR feature tracking study. Inter J Cardiovascular Imaging, 2013, 29(1): 141-150.
[16]
Orwat S, Kempny A, Diller GP, et al. Cardiac magnetic resonance feature tracking- a novel method to assess myocardial strain: Comparison with echocardiographic speckle tracking in healthy volunteers and in patients with left ventricular hypertrophy. Kardiol Pol, 2014, 72(4): 363.

PREV A preliminary study on evaluation of brain damage in acute phase of carbon monoxide intoxication with diffusion kurtosis imaging
NEXT The significance of MRI enhanced scan in the spinal tuberculosis
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn