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• Technical Article •
Variation analysis of diffusion weighted imaging in normal brain tissue between two b and multi-b value sequence
LI Xiang  GAO Peng-rui  ZHANG Shou-ning  ZHANG Hong-kai  QU Jin-rong  LI Hai-liang 

DOI:10.12015/issn.1674-8034.2017.06.010.


[Abstract] Objective: To observe the variation of two b and multi-b diffusion weighted imaging (DWI) in normal brain tissue.Materials and Methods: Apply two b and multi-b DWI sequence to 29 normal appearance brain using GE 3.0 T scanner. Two b and multi-b DWI related parameter including apparent diffusion coefficient (ADC), true diffusion (D), perfusion related diffusion (D*), fraction of perfusion (f) was acquired using AW workstation. The coefficient of variation (CV) of these parameters was compared to evaluate the reliability.Results: The values of CV of ADC, D, D* and f of brain were (81.11±7.62) × 10-5 mm/s, 0.094; (78.47±6.72)×10-5 mm/s, 0.086; (722.7±189.3)×10-5 mm/s, 0.262; (8.97±3.63)%, 0.404 in white matter; and (87.03±9.97)×10-5 mm/s, 0.115; (81.83±7.51)×10-5 mm/s, 0.092; (611.9±169.5)×10-5 mm/s, 0.292; (9.55±3.41)%, 0.357 in gray matter; and (76.70±7.17)×10-5 mm/s, 0.093; (73.72±6.40)×10-5 mm/s, 0.087; (1221.9±743.4)×10-5 mm/s, 0.608; (9.72±3.68%), 0.379 in basal ganglia respectively. The CVs of ADC and D were similar and good and lower than others.Conclusion: D which derived from Multi-b DWI has good reliability as ADC which derived from two b DWI in normal brain. Otherwise, D* and f have higher variation in normal brains, and with which the comparison between individual should be explained with caution.
[Keywords] Magnetic resonance imaging；Diffusion weighted imaging；Coefficient of variation；Brain

LI Xiang Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

GAO Peng-rui Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

ZHANG Shou-ning Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

ZHANG Hong-kai Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

QU Jin-rong Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

LI Hai-liang* Department of Radiology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China

*Correspondence to: Li HL, E-mail: cjr.lihailiang@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Science and Technology Research Project of Henan Province No. 142102310435
Received  2017-01-11
Accepted  2017-04-19
DOI: 10.12015/issn.1674-8034.2017.06.010
DOI:10.12015/issn.1674-8034.2017.06.010.

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