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Quantitative metabolites of lumbar intervertebral disc degeneration by diffusion tensor MR
ZHAO Shuang  PENG Ru-chen  SHEN Xiu-zhi  ZHANG Shuang  ZHONG Jia-li  SONG Hai-long 

DOI:10.12015/issn.1674-8034.2017.06.011.


[Abstract] Objective: To investigate the MR diffusion tensor imaging (DTI) as an application of quantitative analysis methods in lumbar intervertebral disc degeneration and the effects of different diffusion gradient directions (DGD) of DTI.Materials and Methods: Selected 50 patients with pain of waist or legs, including 32 male and 18 female, from 24 to 62 years old with mean age 46.9±16.2 years old, all the patients underwent sagittal scans for regular lumbar MRI and DTI, and with 6, 12, 20 DGD of DTI. According to the DGD, lumbar intervertebral discs can be divided into DD6, DD12, DD20 groups and divided lumbar intervertebral discs into Ⅱ, Ⅲ, Ⅳ, and Ⅴ groups by Pfirrmann grading system. ADC and FA and λ1 valuse were measured and analyzed among the different DGD groups and Pm groups.Results: There were no statistical difference of ADC values among the different DGD groups (P>0.05), while statistical difference of FA and λ1 values were found (P<0.05); DGD for 6, FA values were statistical differences among the different Pm groups (P<0.05), except Ⅳ and Ⅴ(P>0.05); DGD for 12 and 20, there were no statistical difference of FA values in all PM groups (P>0.05), except Ⅱ. DGD for 6, 12, 20, ADC values were statistical difference in all Pm groups, except Ⅱ and Ⅲ. In DGD for 6, 12, 20, λ1 values had no statistical difference in all Pm groups (P>0.05).Conclusion: DTI can be applied to the quantitative analysis of lumbar intervertebral disc, DGD for 6 can get high quality images and data in a relatively short time, and FA value can be used for quantitative analysis of different Pm grading lumbar intervertebral disc.
[Keywords] Magnetic resonance imaging；Diffusion tensor imaging；Intervertebral disc degeneration；Apparent diffusion coefficient

ZHAO Shuang Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

PENG Ru-chen* Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

SHEN Xiu-zhi Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

ZHANG Shuang Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

ZHONG Jia-li Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

SONG Hai-long Department of Radiology, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China

*Correspondence to: Peng RC, E-mail:13501271260@163.com

Conflicts of interest   None.

Received  2017-01-21
Accepted  2017-03-16
DOI: 10.12015/issn.1674-8034.2017.06.011
DOI:10.12015/issn.1674-8034.2017.06.011.

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