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MRI evaluation of hepatic iron overload: recent advances
LIU Hua-ping  LI Wen-zheng  LI Hai-lan  ZHANG You-ming 

DOI:10.12015/issn.1674-8034.2017.06.016.


[Abstract] Iron overload can be caused by hereditary hemochromatosis, hematological diseases, chronic liver disease and so on. Severe iron overload can result in liver, heart, pancreas, thyroid organs, the central nervous system, and other organ dysfunction, or even can cause death. Iron overload can result in liver damage firstly, and the liver iron concentration bring into correspondence with the body iron content. MRI can accurately noninvasive assess and monitor the liver iron concentration, provide guidance for clinical treatment. This article mainly introduces MRI-based methods for quantification of liver iron, including remaining challenges, unsolved problems and potential application prospect.
[Keywords] Liver；Iron overload；Magnetic resonance imaging

LIU Hua-ping Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China

LI Wen-zheng* Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China

LI Hai-lan Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China

ZHANG You-ming Department of Radiology, Xiangya Hospital, Central South University, Changsha 410008, China

*Correspondence to: Li WZ, E-mail:liwenzhenghuazi@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Clinical Research Fund of Xiangya Hospital, Central South University No. 2014L05
Received  2017-02-24
Accepted  2017-04-07
DOI: 10.12015/issn.1674-8034.2017.06.016
DOI:10.12015/issn.1674-8034.2017.06.016.

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