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• Clinical Article •
An initial study using the quantitative parameters of dynamic contrast-enhanced MRI in differential diagnosis for parotid tumors with different pathological types
YU Shun  SHI Qing-lei  SU Jia-wei  BAO Qiang  KU Lei-zhi  ZHENG Xue-ping 

DOI:10.12015/issn.1674-8034.2017.09.003.


[Abstract] Objective: To investigate the value of the quantitative parameters of dynamic contrast-enhanced (DCE) MRI-derived parameters in differential diagnosis for parotid tumor with different pathologic types, in order to provide useful quantitative indicators for accurate preoperative diagnosis of parotid tumors.Materials and Methods: Forty-seven patients with different pathological types of parotid tumors were enrolled and performed DCE-MRI examinations. The region of interest was delineated around the tumor margin, time intensity curve (TIC) and quantitative parameters including Ktrans, Ve, Kep were calculated. The differences of TIC and DCE-MRI-derived quantitative parameters were analyzed among different pathologic type of parotid tumors.Results: (1) Among the 47 patients, the numbers of benign and malignant parotid tumor were 37 and 10. No significant difference was demonstrated about the TIC type between the benign (Type A, B, D: 20. Type C: 17) and malignant parotid tumor (Type A, B, D: 2. Type C: 8) (P>0.05). (2) The Ktrans, Kep values of benign parotid tumor (not included adenolymphoma) were significantly lower than malignant parotid tumor, while the value of Ve was significantly higher than malignant parotid tumor (P<0.05). The Ktrans, Kep values of mix parotid tumor were significantly lower than that of malignant parotid tumor and adenolymphoma (P<0.05). The Ve values of mix parotid tumor were significantly higher than malignant parotid tumor and adenolymphoma (P<0.05). The Ktrans, Kep values of adenolymphoma were significantly higher than malignant parotid tumor (P<0.05). High diagnostic efficiency were demonstrated for Ktrans, Ve, Kep values in differential diagnosis of mix parotid tumor from malignant parotid tumor and adenolymphoma.Conclusions: DCE-MRI derived quantitative parameters can differentiate parotid tumors among different pathological types, especially provides a useful quantitative parameters for the differential diagnosis of parotid tumors which were lack of MRI feature.
[Keywords] Parotid neoplasms；Magnetic resonance imaging

YU Shun* Department of Radiology, Fujian Provincial Hospital of Fujian Medical University, Fuzhou 350001, China

SHI Qing-lei Diagnostic Imaging, Siemens Ltd, Beijing 100102, China

SU Jia-wei Department of Radiology, Fujian Provincial Hospital of Fujian Medical University, Fuzhou 350001, China

BAO Qiang Department of Radiology, Fujian Provincial Hospital of Fujian Medical University, Fuzhou 350001, China

KU Lei-zhi Department of Radiology, Fujian Provincial Hospital of Fujian Medical University, Fuzhou 350001, China

ZHENG Xue-ping Department of Radiology, Fujian Provincial Hospital of Fujian Medical University, Fuzhou 350001, China

*Correspondence to: Yu S, E-mail: 76429310@qq.com

Conflicts of interest   None.

Received  2017-05-09
Accepted  2017-07-26
DOI: 10.12015/issn.1674-8034.2017.09.003
DOI:10.12015/issn.1674-8034.2017.09.003.

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