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• Clinical Article •
Comparative analysis of T2-mapping, 3D-FSE-Cube and conventional sequence in the classification of knee cartilage injury in 3.0 T MRI
FAN Zi-jian  WU Li-ping  REN You-zhong  JU Wen-ping  LIU Xiao-yi  WANG Xian-liang 

DOI:10.12015/issn.1674-8034.2017.09.006.


[Abstract] Objective: To evaluate the value of 3D-FSE-Cube, T2-Mapping and conventional MRI sequences in grading diagnosis of knee cartilage injury.Materials and Methods: In this retrospective study, 63 patients with knee joint trauma or osteoarthritis who underwent not only knee joint MRI but also arthroscopic surgery from March 2016 to December 2016 in our hospital were included. Each knee cartilage injury classification diagnosis was respectively obtained by T2-mapping, 3D-FSE-Cube, conventional sequences and arthroscopy. Taking the classification diagnostic results of arthroscopy as gold standards, the sensitivity and specificity of the three sequences for the knee cartilage injury were calculated and compared.Results: The total sensitivity, specificity and sensitivity of grade Ⅰ and Ⅱ injury for knee cartilage were evaluated among three kinds of MRI sequences, and the differences were statistically significant (P<0.05). While the sensitivity of Ⅲ and Ⅳ grade injury had no significant differences (P>0.05). Further analysis of the results between sequences, the sensitivity of T2-mapping sequence for grade Ⅰ knee cartilage injury was significantly higher than that of 3D-FSE-Cube sequence (P<0.0125). There was no significant difference in total sensitivity, specificity and sensitivity of grade Ⅱ injury for knee cartilage between T2-mapping and 3D-FSE-Cube sequence (P>0.0125). As for the total sensitivity and sensitivity of grade Ⅰ and Ⅱ injury, T2-mapping sequence and 3D-FSE-Cube sequence were both higher than that of the conventional sequence, while the specificity of T2-mapping sequence and 3D- FSE-Cube sequence in diagnosis of the knee cartilage injury was lower than that of conventional sequences, the differences were statistically significant (P<0.0125).Conclusions: In the evaluation of knee cartilage injury, the sensitivity of T2-mapping sequence and 3D-FSE-Cube sequence were higher than that of conventional sequence, and the specificity of the conventional sequences was higher than that of T2-mapping sequence and 3D-FSE-Cube sequence. The T2-mapping sequence can indicate early articular cartilage injury without morphology change, which has a high clinical value to diagnose and treat early cartilage injury.
[Keywords] Cartilage, articular；Knee injuries；Magnetic resonance imaging；Arthroscopes

FAN Zi-jian Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

WU Li-ping Department of Radiology, Maternal and Child Health Hospital of Zaozhuang, Zaozhuang 277100, China

REN You-zhong Department of Radiology, the People's Hospital of Weifang, Weifang 261041, China

JU Wen-ping Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

LIU Xiao-yi Department of Medical Imaging of Weifang Medical University, Weifang 261053, China

WANG Xian-liang* Department of Radiology, the People's Hospital of Weifang, Weifang 261041, China

*Correspondence to: Wang XL, E-mail: wangxianliang2011@126.com

Conflicts of interest   None.

Received  2017-04-24
Accepted  2017-08-15
DOI: 10.12015/issn.1674-8034.2017.09.006
DOI:10.12015/issn.1674-8034.2017.09.006.

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