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• Clinical Article •
MRI evaluation of pituitary macroadenomas tumor consistency
WU Chun-xue  MENG Ming  WANG Zheng  WANG Zhao-zhao  CHEN Xu-zhu  LI Chu-zhong  MA Jun 

DOI:10.12015/issn.1674-8034.2017.10.001.


[Abstract] Objective: To assess the role of the preoperative MR signal in predicting the tumor consistency of pituitary macroadenomas.Materials and Methods: According to the surgical findings, 120 pituitary macroadenomas were divided into three types: hard, soft and mixed type. Patient’s age, maximum diameter of tumor, the ratios of signal intensity of tumor to the white matter of temporal lobe in solid tumors were compared in different types. Surgical approach and resection degree in three types tumors were analyzed comparatively. Categorical variables were examined with the chi-square; continuous-scale data were analyzed with the analysis of variance.Results: 12 of 13 non-solid tumors were soft. All non-solid tumors received total or subtotal transsphenoidal hypophysectomy. In 107 solid tumors, the ratios of T2-weighted signal intensity of tumors to the white matter of temporal lobe in soft type was higher than other types (P=0.005, 0.000, respectively). Resection degree of soft tumors was higher than hard tumors (χ2=14.13, P=0.003).Conclusion: The ratios of T2-weighted signal intensity of pituitary macroadenomas to the white matter can be used as an indicator to preoperatively assess the consistency of pituitary tumors, which can help to find the appropriate surgical approach.
[Keywords] Magnetic resonance imaging；Pituitary macroadenomas；Consistency；Surgical approach

WU Chun-xue Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

MENG Ming Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

WANG Zheng Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

WANG Zhao-zhao Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

CHEN Xu-zhu Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

LI Chu-zhong Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

MA Jun* Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China

*Correspondence to: Ma J, E-mail: dr_ma@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 61771325 National High Technology Research and Development Program of China No. 2015AA020504
Received  2017-05-15
Accepted  2017-09-06
DOI: 10.12015/issn.1674-8034.2017.10.001
DOI:10.12015/issn.1674-8034.2017.10.001.

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