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• Clinical Article •
Comparative study on contrast-enhanced Cube FLAIR and T1WI sequences in craniocerebral diseases
ZHANG Le-le  WANG Xiao-ming 

DOI:10.12015/issn.1674-8034.2017.10.002.


[Abstract] Objective: To evaluate the diagnostic value of applying MR contrast-enhanced T1 weighted imaging and T2WI FLAIR CUBE sequence to diagnosis of craniocerebral diseases.Materials and Methods: Twenty-five subjects were included in this study. The patients were composed of 20 cases of single brain tumor, 2 cases of meningitis, and 3 cases of metastatic encephaloma. Twenty-five patients underwent T2 FLAIR, enhanced T1WI and enhanced sagittal Cube FLAIR imaging with the 3.0 T MR scanner. Multi-planar reconstruction and axial reconstruction were completed after enhanced Cube FLAIR scan in order to compare with enhanced T1WI sequence.Results: The signal ratios of lesion had significant difference in enhanced T1WI and enhanced Cube FLAIR (P<0.05), as well as enhanced Cube FLAIR and unenhanced T2 FLAIR (P<0.01). One patient diagnosed with cerebellopontine angle tumor presented with a 6-month history of a facial palsy. We could see clearly about the incrassate facial nerve, which is invisible on the other sequences. Compared with T2 FLAIR and enhanced T1WI, enhanced Cube FLAIR clearly demonstrated the scope of lesions. The enhanced Cube FLAIR sequence clearly depicted the distribution of metastatic lesions and the meningeal spread in the metastatic encephaloma patients as well as a much wider range compared with conventional enhanced T1WI.Conclusion: Enhanced Cube FLAIR sequence can be used as a conventional sequence in the diagnosis of central nervous diseases.
[Keywords] Brain diseases；Brain neoplasms；Magnetic resonance imaging

ZHANG Le-le Shengjing Hospital of China Medical University, Shenyang 110004, China

WANG Xiao-ming* Shengjing Hospital of China Medical University, Shenyang 110004, China

*Correspondence to: Wang XM, E-mail: wangxm024@163.com

Conflicts of interest   None.

Received  2016-05-20
Accepted  2016-08-02
DOI: 10.12015/issn.1674-8034.2017.10.002
DOI:10.12015/issn.1674-8034.2017.10.002.

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