Share：
Share this content in WeChat
X
[Chinese][PDF]78097
• Review •
Advances of quantitative dynamic contrast enhanced MRI in frequent neoplasms of uterus
ZHOU Wei  LÜ Fu-rong 

DOI:10.12015/issn.1674-8034.2017.10.014.


[Abstract] As a new functional imaging evaluation method, quantitative dynamic contrast enhanced MRI, not only provide the morphological information, but also evaluate tumor microenvironment so that indirectly assess tumor's blood vessel growth by some parameters of perfusion and permeability. This method has assist in diagnosis of uterine tumor, choice of treatment, evaluation of therapeutic effect and judgement of the prognosis. People have paid more attention to the application of quantitative dynamic contrast enhanced MRI in the uterine tumors. The application and progress of quantitative dynamic contrast enhanced MRI in frequent neoplasms of uterus were reviewed in the present paper.
[Keywords] Magnetic resonance imaging；Quantitative analysis；Uterine neoplasms

ZHOU Wei Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

LÜ Fu-rong* Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

*Correspondence to: LÜ FR, E-mail: lfr918@sina.com

Conflicts of interest   None.

Received  2017-08-02
Accepted  2017-09-06
DOI: 10.12015/issn.1674-8034.2017.10.014
DOI:10.12015/issn.1674-8034.2017.10.014.

[1]
Van Niekerk CG, van der Laak JA, Hambrock T, et al. Correlation between dynamic contrast-enhanced MRI and quantitative histopathologic microvascular parameters in organ-confined prostate cancer. Eur Radiol, 2014, 24(10): 2597-2605.
[2]
赵飞飞，吕富荣，肖智博,等.动态增强MRI Reference region模型在子宫肌瘤中的初步应用.中国医学影像技术, 2015, 31(12):1861-1865.
[3]
Rata M, Collins DJ, Darcy J, et al. Assessment of repeatability and treatment response in early phase clinical trials using DCE-MRI: comparison of parametric analysis using MR- and CT-derived arterial input functions. Eur Radiol, 2016, 26(7): 1991-1998.
[4]
Punwani S. Contrast enhanced MR imaging of female pelvic cancers: established methods and emerging applications. Eur J Radiol, 2011,78(1): 2-11.
[5]
张庆，徐香玖，周星,等. 3.0 T MR动态对比增强对宫颈癌组织学特性和临床分期的分析.临床放射学杂志, 2015, 34(10): 1607-1610.
[6]
Wang N, Zhan T, Ke T, et al. Increased expression of RRM2 by human papillomavirus E7 oncoprotein promotes angiogenesis in cervical cancer. Br J Cancer, 2014, 110(4): 1034-1044.
[7]
Gordon Y, Partovi S, Müller-Eschner M, et al. Dynamic contrast-enhanced magnetic resonance imaging: fundamentals and application to the evaluation of the peripheral perfusion. Cardiovasc Diagn Ther, 2014, 4(2): 147-164.
[8]
周星，黄刚，张庆,等.动态增强MRI及扩散加权成像对宫颈癌病理特征及临床分期的应用.中国医学影像学杂志, 2016, 24(11):855-860.
[9]
Qu H, Ning G, Li X, et al. Study on correlations between CT perfusion parameters and tumor angiogehesis of cervical cancer. J Biomedical Eng, 2013, 30(2): 254-259.
[10]
张朝赫，罗娅红，于韬,等.宫颈鳞癌DCE-MRI动态增强灌注参数测量的可重复性以及与病理临床特征的相关性.现代肿瘤医学,2017, 25(8): 1274-1278.
[11]
周延，刘剑羽，刘从容,等. MR体素内不相干运动成像用于评价宫颈癌恶性程度和组织血供的价值.中华放射学杂志, 2015, 49(5):354-359.
[12]
Haldorsen T, Skare GB, Ursin G, et al. Results of delayed triage by HPV testing and cytology in the norwegian cervical cancer screening programme. Acta Oncol, 2015, 54(2): 200-209.
[13]
刘伟锋，徐凡，吴梅. DCE-MRI 4D-Tissue技术定量参数评估宫颈癌放化疗疗效的预测价值.实用肿瘤学杂志, 2016, 30(3): 225-228.
[14]
Ellingsen C, Hompland T, Galappathi K, et al. DCE-MRI of the hypoxic fraction, redioresponsiveness, and metastatic propensity of cervical carcinoma xenografts. Radiother Oncol, 2014, 110(2): 335-341.
[15]
Park JJ, Kim CK, Park SY, et al. Assessment of early response to concurrent chemoradiotherapy in cervical cancer: value of diffusion-weighted and dynamic contrast-enhanced MR imaging. Magn Reson Imaging, 2014, 32(8): 993-1000.
[16]
Mills SJ, Soh C, Rose CJ, et al. Candidate biomarkers of extravascular space: A direct comparison of apparent diffusion coefficient and dynamic contrast-enhanced MR imaging-derived measurement of the volume of the extravascular space in glioblastoma multiforme. AJNR, 2010, 31(3): 549-553.
[17]
Zahra MA, Tan LT, Priest AN, et al.Semiquantitative and quantitative dynamic contrast-enhanced magnetic resonance imaging measurements predict radiation response in cervical cancer. Int J Radiat Oncol Biol Phys, 2009, 74(3): 766-773.
[18]
Himoto Y, Fujimoto K, Kido A, et al. Assessment of the early predictive power of quantitative magnetic resonace imaging parameters during neoadjuvant chemotherapy for urterine cervical cancer. Int J Gynecol Cancer, 2014, 24(4): 751-757.
[19]
Kim JH, Kim CK, Park BK, et al. Dynamic contrastenhanced 3.0 T MR imaging in cervical cancer before and after concurrent chemoradiotherapy. Eur Radiol, 2012, 22(11): 2533-2539.
[20]
Andersen EK, Hole KH, Lund KV, et al. Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome. Radiother Oncol, 2013, 107(1): 117-122.
[21]
朱志军，张碧娟，郭吉敏,等.动态增强MRI微血管通透性参数与Ⅱ期宫颈癌复发的相关性研究.放射学实践, 2015, 30(8): 841-844.
[22]
Lollert A, Junginger T, Schimanski CC, et al. Rectal cancer: dynamic contrast-enhanced MRI correlates with lymph node status and epidermal growth factor receptor expression. J Magn Reson Imaging, 2014, 39(6): 1436-1442.
[23]
杨晓棠，张建新，杜笑松,等.动态增强MRI定量与半定量分析在直肠癌术前T、N分期中的应用价值.中华解剖与临床杂志, 2016,21(2): 109-114.
[24]
刘梦秋.宫颈癌磁共振动态增强定量参数与ADC值的相关性研究.合肥:安徽医科大学, 2015.
[25]
Kundu S, Chopra S, Verma A, et al. Functional magnetic resonance imaging in cervical cancer: Current evidence and future directions. J Cancer Res Ther, 2012, 8(1): 11-18.
[26]
何永红，林祺，詹泽娟,等.宫颈癌扩散加权成像表观扩散系数与磁共振动态增强定量参数的临床价值.磁共振成像, 2016, 7(12):926-931.
[27]
Emlik D, Kiresi D, Ozdemir S, et al. Preoperative assessment of myometrial and cervical invasion in endometrial carcinoma: comparison of multi-section dynamic MR imaging using a three dimensional FLASH technique and T2-weighted MR imaging. J Med Imaging Radiat Oncol, 2010, 54(3): 202-210.
[28]
Haldorsen IS, Grüner R, Husby JA, et al. Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence. Eur Radiol, 2013, 23(10): 2916-2925.
[29]
郭永梅，尹进学，江新青,等. DCE-MRI定量参数分析子宫内膜癌影像与病理特征相关性研究.临床放射学杂志, 2016, 35(10):1546-1550.
[30]
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer J Clin, 2015, 65(1): 5-29.
[31]
薛康康，程敬亮，白洁,等. DWI及动态增强MRI鉴别诊断子宫肉瘤与变性子宫肌瘤的价值.中国医学影像技术, 2016, 32(2):274-278.
[32]
Yang Q, Diamond MP, Al-Hendy A. Early life adverse environmental exposures increase the risk of uterine fibroid development: role of epigenetic regulation. Front Pharmacol, 2016, 7(e99800): 40.
[33]
郑静，赵振华，胡红杰,等. Extended Tofts与Exchange模型的动态对比增强MRI参数在鉴别细胞型子宫肌瘤中应用.临床放射学杂志, 2017, 36(5): 687-691.
[34]
Tal R, Segars JH. The role of angiogenic factors in fibroid pathogenesis: potential implications for future therapy. Human Reproduction Update, 2014, 20(2): 194-216.
[35]
王玉玲，柳晓春，谢庆煌,等.雌激素受体、孕激素受体、血管内皮生长因子及其受体在宫肌瘤中的表达和临床研究.实用妇产科杂志, 2010, 26(6): 436-438.
[36]
Fadare O, Renshaw I, Olson SJ, et al. The phosphatidylinositol 3'kinase-Akt-mammalian target of rapamycin pathway in smooth muscle tumors of the uterus: selected protein expression patterns and their clinicopathologic implications. Int J Gynecol Pathol, 2011,30(3): 244-251.
[37]
王伟，张暹东，李祎,等.动态增强磁共振成像定量参数对子宫肌瘤高强度聚焦超声治疗效果的即时评估价值初探.磁共振成像,2015, 6(8): 603-607.
[38]
韦超，董江宁，方昕,等. DCE-MRI定量参数预测高强度超声消融术治疗症状性子宫肌瘤首次体积消融率价值.临床放射学杂志, 2016, 35(4): 545-550.
[39]
刘柳恒，吕富荣，肖智博,等.动态增强MRI定量参数与高强度聚焦超声消融子宫肌瘤疗效的相关性研究.临床放射学杂志, 2017,36(7): 1024-1028.
[40]
Kim YS, Lim HK, Kim JH, et al. Dynamic contrast enhanced magnetic resonance imaging predicts immediate therapeutic response of magnetic resonance-guided high-intensity focused ultrasound ablation of symptomatic uterine fibroids. Invest Radiol, 2011, 46(10):639-647.
[41]
Zhao WP, Chen JY, Chen WZ. Dynamic contrast-enhanced MRI serves as a predictor of HIFU treatment outcome for uterine fibroids with hyperintensity in T2-weighted images. Exp Ther Med, 2016,11(1): 328-334.
[42]
Kim YS, Kim JH, Rhim H, et al. Volumetric MR-guided high-intensity focused ultrasound ablation with a one-layer strategy to treat large uterine fibroids: initial clinical outcomes. Radiology, 2012,263(2): 600-609.
[43]
Liu J, Keserci B, Yang X, et al. Volume transfer constant (Ktrans) maps from dynamic contrast enhanced MRI as potential guidance for MR-guided high intensity focused ultrasound treatment of hypervascular uterine fibroids. Magn Reson Imaging, 2014, 32(9): 1156-1161.
[44]
郭永梅，江新青，刘国顺,等.动态增强MRI半定量信号强度-时间曲线及全定量灌注参数在子宫肿瘤中的应用.中南大学学报(医学版), 2015, 40(12): 1357-1364.
[45]
孙俊旗，吴光耀，单菲菲,等.定量MRI动态增强成像定量参数和灌注参数在宫颈癌微循环评价的价值.牡丹江医学院学报, 2016,37(4): 1-5.

PREV Advances of diagnosis and treatment evaluation of intrahepatic cholangiocarcinoma in magnetic resonance imaging
NEXT Cerebral perfusion varieties using 3D pseudo-continuous arterial spin labeling with different PLD in patients with unilateral middle cerebral artery stenosis or occlusion
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn