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• Clinical Article •
The value of susceptibility weighted imaging in the identification of necrotic glioblastomas and brain abscesses
MA Lun  BAI Yan  LIU Tai-yuan  MA Xiao-yue  DOU She-wei  WANG Mei-yun 

DOI:10.12015/issn.1674-8034.2017.11.004.


[Abstract] Objective: To investigate the value of susceptibility weighted imaging (SWI) in differentiating the necrotic glioblastomas and brain abscesses.Materials and Methods: Twenty-three patients with necrotic glioblastomas and 16 patients with brain abscesses were retrospectively analyzed. All patients underwent conventional MRI and SWI on a 3.0 T MR unit. To evaluate the value of SWI in differentiating the necrotic glioblastomas and brain abscesses by detecting the intralesional susceptibility signal (ILSS).Results: Twenty-two (95.7%) of 23 patients with necrotic glioblastomas were detected with ILSS. Six (37.5%) of 16 patients with brain abscesses were detected with ILSS. The sensitivity of ILSS in differentiating necrotic glioblastomas and brain abscesses patients was 96% and the specificity was 63%. The detection rate of ILSS in patients with necrotic glioblastomas was higher than that in patients with brain abscesses (OR=36.67, P=0.002).Conclusion: SWI has great value in differentiating the necrotic glioblastomas and brain abscesses.
[Keywords] Susceptibility weighted imaging；Glioblastoma；Brain abscess；Intralesional susceptibility signal

MA Lun Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China

BAI Yan Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China; Henan Key Laboratory for Medical Imaging of Neurological Disease, Zhengzhou 450003, China

LIU Tai-yuan Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China

MA Xiao-yue Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China; Henan Key Laboratory for Medical Imaging of Neurological Disease, Zhengzhou 450003, China

DOU She-wei Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China

WANG Mei-yun* Department of Radiology, Zhengzhou University People’s Hospital, Zhengzhou 450003, China; Henan Key Laboratory for Medical Imaging of Neurological Disease, Zhengzhou 450003, China.; Henan Provincial Clinical Big Data Analysis and Service Engineering Research Center, Henan Provincial People's Hospital, Zhengzhou, 450003, China

*Correspondence to: Wang MY, E-mail: mywang@ha.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  Supported by National Natural Science Foundation No. 81641168, 31470047, 81271565, 81601466 Henan Province Scientific and Technological Innovation Talents Project No. 164200510014 Henan Province Scientific and Technological Open and Cooperating Project No. 152106000014 Henan Province Medical Scientific and Technological Research Project No. 201501011
Received  2017-06-18
Accepted  2017-08-15
DOI: 10.12015/issn.1674-8034.2017.11.004
DOI:10.12015/issn.1674-8034.2017.11.004.

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