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• Clinical Article •
The comparison of sagittal full field-of-view and reduced field-of-view intravoxel incoherent motion imaging of spinal bone marrow
XING Dong  ZHA Yun-fei  LIU Fang  LI Liang  GONG Wei  HU Lei  LIN Yuan  LU Xue-song  LIU Chang-sheng 

DOI:10.12015/issn.1674-8034.2017.12.004.


[Abstract] Objective: The purpose of this study is to compare image quality and the intravoxel incoherent motion (IVIM) parameters obtained with full FOV or reduced FOV IVIM imaging.Materials and Methods: Twenty-six healthy volunteers (12 male, 14 female) with age of 41.12±14.96 years (Mean±SD) were enrolled in this retrospective study. The lumbar imaging protocol included routine imaging, rFOV IVIM DWI (FOV 32 cm×12.8 cm, b=0 s/mm2, 15 s/mm2, 30 s/mm2, 50 s/mm2, 70 s/mm2, 100 s/mm2, 300 s/mm2, 500 s/mm2, 800 s/mm2) and fFOV IVIM DWI (FOV 32 cm×32 cm, b=0 s/mm2, 15 s/mm2, 30 s/mm2, 50 s/mm2, 70 s/mm2, 100 s/mm2, 300 s/mm2, 500 s/mm2, 800 s/mm2). Raw rFOV and fFOV IVIM DWI data were post-processed by Functool provided in Advantage Workstation (version 4.6, GE), and each vertebral body was selected as a region of interest (ROI). Image quality of rFOV and fFOV IVIM DW images were qualitatively evaluated by using a 5-point likert scale. IVIM DWI distortion was quantitatively evaluated by calculating the distortion rate of L3 vertebral body. The quantitative measurements and qualitative scores of IVIM DW images were performed by two radiologists who were blinded to the clinical and sequences information, and the consistency of the two readers was evaluated, and the mean IVIM parameters, qualitative scores, and distortion ratios of the two readers were calculated. The IVIM parameters (ADCfast, ADCslow, f), qualitative scores, and distortion ratios of the two IVIM DWI were compared with paired t-test or Wilcoxon's test according to the Kolmogorov-Smirnov test.Results: In this study, there was good inter reader agreement in IVIM parameters, qualitative scores and distortion rate of rFOV-IVIM DWI and fFOV IVIM DWI. Statistically significant differences in ADCfast (t=-9.92, P<0.01), ADCslow (Z=-2.20, P<0.05), f (t=-17.86, P<0.01), image quality scores (Z=-12.76, P<0.01), area distortion rate (Z=-4.27, P<0.01), and anteroposterior distances distortion rate (Z=-6.20, P<0.01) between rFOV and fFOV IVIM DWI was observed, while no significant difference in craniocaudal distances distortion rate (t=-0.50, P=0.62) between rFOV and fFOV IVIM DWI was observed.Conclusions: Compared with fFOV IVIM, rFOV IVIM DW images of spine bone marrow show improved image quality, and rFOV IVIM technique of spine may help to obtain relatively accurate IVIM parameters.
[Keywords] Full field of view；Reduced field of view；Intravoxel incoherent motion；Spinal bone marrow；Magnetic resonance imaging

XING Dong Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

ZHA Yun-fei* Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China; Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment, Wuhan 430074, China

LIU Fang Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

LI Liang Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

GONG Wei Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

HU Lei Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

LIN Yuan Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

LU Xue-song Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment, Wuhan 430074, China; School of Biomedical Engineering, South-Central University for Nationalities, Wuhan 430074, China

LIU Chang-sheng Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China

*Correspondence to: Zha YF, E-mail: zhayunfei999@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Opening Foundation of Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment No. PJS140011511 Scientific Research Funding Project of Hubei Provincial Department of Health No. JX6B68
Received  2017-06-12
Accepted  2017-09-06
DOI: 10.12015/issn.1674-8034.2017.12.004
DOI:10.12015/issn.1674-8034.2017.12.004.

[1]
Iima M, Le Bihan D. Clinical intravoxel incoherent motion and diffusion MR imaging: past, present, and future. Radiology, 2016,278(1): 13-32.
[2]
Marchand AJ, Hitti E, Monge F, et al. MRI quantification of diffusion and perfusion in bone marrow by intravoxel incoherent motion (IVIM) and non-negative least square (NNLS) analysis. Magn Reson Imaging, 2014, 32(9): 1091-1096.
[3]
Bourillon C, Rahmouni A, Lin C, et al. Intravoxel incoherent motion diffusion-weighted imaging of multiple myeloma lesions: correlation with whole-body dynamic contrast agent-enhanced MR imaging. Radiology, 2015, 277(3): 773-783.
[4]
Niu J, Li W, Wang H, et al. Intravoxel incoherent motion diffusion-weighted imaging of bone marrow in patients with acute myeloid leukemia: a pilot study of prognostic value. J Magn Reson Imaging, 2017. DOI: 10.1002/jmri.25600.
[5]
Baik JS, Jung JY, Jee WH, et al. Differentiation of focal indeterminate marrow abnormalities with multiparametric MRI. J Magn Reson Imaging, 2017, 46(1): 49-60.
[6]
Gaeta M, Benedetto C, Minutoli F, et al. Use of diffusion-weighted, intravoxel incoherent motion, and dynamic contrast-enhanced MR imaging in the assessment of response to radiotherapy of lytic bone metastases from breast cancer. Acad Radiol, 2014, 21(10):1286-1293.
[7]
Koh DM, Collins DJ, Orton MR. Intravoxel incoherent motion in body diffusion-weighted MRI: reality and challenges. AJR Am J Roentgenol, 2011, 196(6): 1351-1361.
[8]
Bhosale P, Ramalingam P, Ma J, et al. Can reduced field-of-view diffusion sequence help assess microsatellite instability in FIGO stage 1 endometrial cancer?. J Magn Reson Imaging, 2017, 45(4):1216-1224.
[9]
Saritas EU, Cunningham CH, Lee JH, et al. DWI of the spinal cord with reduced FOV single-shot EPI. Magn Reson Med, 2008, 60(2):468-473.
[10]
Lu Y, Hatzoglou V, Banerjee S, et al. Repeatability investigation of reduced field of view diffusion-weighted magnetic resonance imaging on thyroid glands. J Comput Assist Tomogr, 2015, 39(3):334-339.
[11]
Kida I, Ueguchi T, Matsuoka Y, et al. Comparison of diffusion-weighted imaging in the human brain using readout-segmented EPI and PROPELLER turbo spin echo with single-shot EPI at 7 T MRI. Invest Radiol, 2016, 51(7): 435-439.
[12]
邹明珠，朱捷，周诚,等.正常腰椎MRI体素不相干运动成像中轴位及矢状位扫描对骨髓各参数一致性的影响.医学影像学杂志, 2016, 26(6): 1065-1067, 1075.
[13]
Hilbert F, Wech T, Neubauer H, et al. Comparison of turbo spin echo and echo planar imaging for intravoxel incoherent motion and diffusion tensor imaging of the kidney at 3.0 Tesla. Z Med Phys, 2017, 27(3): 193-201.
[14]
Andre JB, Zaharchuk G, Saritas E, et al. Clinical evaluation of reduced field-of-view diffusion-weighted imaging of the cervical and thoracic spine and spinal cord. AJNR Am J Neuroradiol, 2012,33(10): 1860-1866.
[15]
Zaharchuk G, Saritas EU, Andre JB, et al. Reduced field-of-view diffusion imaging of the human spinal cord: comparison with conventional single-shot echo-planar imaging. AJNR Am J Neuroradiol, 2011, 32(5): 813-820.
[16]
Radhakrishnan R, Betts AM, Care MM, et al. Reduced field of view diffusion-weighted imaging in the evaluation of congenital spine malformations. J Neuroimaging, 2016, 26(3): 273-277.
[17]
Yoon MA, Hong SJ, Lee CH, et al. Intravoxel incoherent motion (IVIM) analysis of vertebral bone marrow changes after radiation exposure from diagnostic imaging and interventional procedures. Acta Radiol, 2017, 58(10): 1260-1268.
[18]
赵强，周广金，和清源,等.小视野扩散加权成像技术在脊柱及脊髓病变中的应用.磁共振成像, 2012, 3(4): 275-277.
[19]
Guo T, Chen J, Wu B, et al. Use of intravoxel incoherent motion diffusion-weighted imaging in identifying the vascular and avascular zones of human meniscus. J Magn Reson Imaging, 2017, 45(4):1090-1096.
[20]
余浩，王梓，王艳春,等.常规视野与小视野IVIM扩散加权成像在正常胰腺的对比研究.影像诊断与介入放射学, 2015, 24(6):491-496.

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