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• Clinical Article •
Application of intravoxel incoherent motion imaging of 3.0 T magnetic resonance imaging on the identification rectal tubulovillous adenoma and rectal cancer
WANG Ling-hua  LI Yong-gang 

DOI:10.12015/issn.1674-8034.2017.12.007.


[Abstract] Objective: To evaluate the role of differential diagnosis of 3.0 T intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI) on rectal tubulovillous adenoma and rectal cancer.Materials and methods: 11 cases of rectal tubulovillous adenoma and 30 cases of rectal cancer patients (confirmed by pathology) were enrolled in this study between June 2016 and June 2017 at the First Affiliated Hospital of Soochow University 3.0 T MRI normal sequences and IVIM examination in the two groups before surgery. Perfusion-related diffusion coefficient (D), real diffusion coefficient (D*), perfusion fraction (f) and apparent diffusion coefficient (ADC) were measured on the post-processing software, and D, D*, f and ADC values were compared respectively to analyze the diagnosis efficiency of each parameter of rectal tubulovillous adenoma and rectal cancer.Results: The D value and standard ADC value of rectal cancer group were lower than those of rectal tubulovillous adenoma group, and the difference was statistically significant (all P<0.05). The mean value of D* was higher than that of rectal tubulovillous adenoma group, but the difference was not statistically significant (P>0.05). There was no significant difference between the two groups (P>0.05). The cut-off value for rectal tubulovillous adenoma and rectal cancer was ADC<1.026×10-3 mm2/s, the sensitivity and specificity was 81.8%, 70%; D<0.788×10-3 mm2/s, the sensitivity and specificity was 87.9%, 71.1%.Conclusions: D and ADC value have reference value for identification of diagnosis of rectal cancer and rectal tubulovillous adenoma.
[Keywords] Intravoxel incoherent motion；Rectal neoplasms；Tubulovillous adenoma；Magnetic resonance imaging

WANG Ling-hua Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China

LI Yong-gang* Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China

*Corresponding to: Li YG, E-mail: liyonggang224@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81671743
Received  2017-08-18
Accepted  2017-10-23
DOI: 10.12015/issn.1674-8034.2017.12.007
DOI:10.12015/issn.1674-8034.2017.12.007.

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