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Application and development of arterial spin labeling technique of magnetic resonance imaging in cerebrovascular disease
ZHANG Hui-qin  LI Ming-li 

DOI:10.12015/issn.1674-8034.2017.12.012.


[Abstract] Arterial spin labeling (ASL) is a functional MRI technique that can noninvasively assess cerebral blood flow using blood as an endogenous contrast agent. In this article, the clinical application of ASL technology in cerebrovascular disease will be reviewed. In transient ischemic attack, ASL can be sensitive to the brain perfusion abnormalities. In acute cerebral infarction, ASL can be used to assess ischemic penumbra, identify arterial occlusion of the arteries, and detect high perfusion around the infarct area. In the chronic cerebrovascular disease, multi-ASL technique can assess cerebral blood flow more accurately than before; two-stage ASL technology can assess collateral blood vessels quantitatively, also ASL can be used to assess cerebrovascular reserve. In moyamoya disease, ASL technology can assess the preoperative and postoperative perfusion and collateral blood vessels. The final statement is about ASL technology in cerebrovascular malformations and reversible posterior encephalopathy application. In the final part, current limitations and future developments of ASL techniques will be reviewed.
[Keywords] Arterial spin labeling；Magnetic resonance imaging；Perfusion weighted imaging；Cerebrovascular disease；Cerebral blood flow

ZHANG Hui-qin Department of Radiology, Peking Union Medical College Hospital of Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100730, China

LI Ming-li* Department of Radiology, Peking Union Medical College Hospital of Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100730, China

*Correspondence to: Li ML, E-mail: pumclml@126.com

Conflicts of interest   None.

Received  2017-07-19
Accepted  2017-09-06
DOI: 10.12015/issn.1674-8034.2017.12.012
DOI:10.12015/issn.1674-8034.2017.12.012.

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