Share：
Share this content in WeChat
X
[Chinese][PDF]70297
• Review •
Application and development of arterial spin labeling technique of magnetic resonance imaging in cerebrovascular disease
ZHANG Hui-qin  LI Ming-li 

DOI:10.12015/issn.1674-8034.2017.12.012.


[Abstract] Arterial spin labeling (ASL) is a functional MRI technique that can noninvasively assess cerebral blood flow using blood as an endogenous contrast agent. In this article, the clinical application of ASL technology in cerebrovascular disease will be reviewed. In transient ischemic attack, ASL can be sensitive to the brain perfusion abnormalities. In acute cerebral infarction, ASL can be used to assess ischemic penumbra, identify arterial occlusion of the arteries, and detect high perfusion around the infarct area. In the chronic cerebrovascular disease, multi-ASL technique can assess cerebral blood flow more accurately than before; two-stage ASL technology can assess collateral blood vessels quantitatively, also ASL can be used to assess cerebrovascular reserve. In moyamoya disease, ASL technology can assess the preoperative and postoperative perfusion and collateral blood vessels. The final statement is about ASL technology in cerebrovascular malformations and reversible posterior encephalopathy application. In the final part, current limitations and future developments of ASL techniques will be reviewed.
[Keywords] Arterial spin labeling；Magnetic resonance imaging；Perfusion weighted imaging；Cerebrovascular disease；Cerebral blood flow

ZHANG Hui-qin Department of Radiology, Peking Union Medical College Hospital of Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100730, China

LI Ming-li* Department of Radiology, Peking Union Medical College Hospital of Chinese Academy of Medical Sciences and Beijing Union Medical College, Beijing 100730, China

*Correspondence to: Li ML, E-mail: pumclml@126.com

Conflicts of interest   None.

Received  2017-07-19
Accepted  2017-09-06
DOI: 10.12015/issn.1674-8034.2017.12.012
DOI:10.12015/issn.1674-8034.2017.12.012.

[1]
Noguchi T. A technical perspective for understanding quantitative arterial spin-labeling MR imaging using continuous ASL. Pol J Radiol, 2016, 81(1): 317-321.
[2]
Grade M, Hernandez Tamames JA, Pizzini FB, et al. A neuroradiologist's guide to arterial spin labeling MRI in clinical practice. Neuroradiology, 2015, 57(12): 1181-1202.
[3]
Krainik A, Villien M, Troprès I, et al. Functional imaging of cerebral perfusion. Diagn Interv Imaging, 2013, 94(12): 1259-1278.
[4]
Zun Z, Shankaranarayanan A, Zaharchuk G. Pseudocontinuous arterial spin labeling with prospective motion correction (PCASL-PROMO). Magn Reson Med, 2014, 72(4): 1049-1056.
[5]
Alsop DC, Detre JA, Golay X, et al. Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. Magn Reson Med, 2015, 73(1):102-116.
[6]
Wang DJJ, Alger JR, Qiao JX, et al. Multi-delay multi-parametric arterial spin-labeled perfusion MRI in acute ischemic stroke: Comparison with dynamic susceptibility contrast enhanced perfusion imaging. NeuroImage: Clinical, 2013, 3(3): 1-7.
[7]
Fujiwara Y, Matsuda T, Kanamoto M, et al. Comparison of long-labeled pseudo-continuous arterial spin labeling (ASL) features between young and elderly adults: special reference to parameter selection. Acta Radiol, 2016, 58(1): 84-90.
[8]
Easton JD, Saver JL, Albers GW, et al. Definition and evaluation of transient ischemic attack: A scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease: The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke, 2009, 40(6): 2276-2293.
[9]
Zaharchuk G, Olivot J, Fischbein NJ, et al. Arterial spin labeling imaging findings in transient ischemic attack patients: comparison with diffusion- and bolus perfusion-weighted imaging. Cerebrovascular Dis, 2012, 34(3): 221-228.
[10]
Qiao XJ, Salamon N, Wang DJJ, et al. Perfusion deficits detected by arterial spin-labeling in patients with TIA with negative diffusion and vascular imaging. AJNR Am J Neuroradiol, 2013, 34(11):2125-2130.
[11]
Lin L, Bivard A, Krishnamurthy V, et al. Whole-brain CT perfusion to quantify acute ischemic penumbra and core. Radiology, 2016,279(3): 876-887.
[12]
Wang DJJ, Alger JR, Qiao JX, et al. The value of arterial spin-labeled perfusion imaging in acute ischemic stroke-comparison with dynamic susceptibility contrast enhanced MRI. Stroke, 2012, 43(4):1018-1024.
[13]
Niibo T, Ohta H, Yonenaga K, et al. Arterial spin-labeled perfusion imaging to predict mismatch in acute ischemic stroke. Stroke, 2013,44(9): 2601-2603.
[14]
邢飞，邢伟，卢又燃,等.动脉自旋标记与动态磁敏感对比MRI在脑卒中缺血半暗带的对照研究.中国医学计算机成像杂志, 2014,20(2): 110-115.
[15]
Nael K, Meshksar A, Liebeskind DS, et al. Quantitative analysis of hypoperfusion in acute stroke: arterial spin labeling versus dynamic susceptibility contrast. Stroke, 2013, 44(11): 3090-3096.
[16]
Majer M, Mejdoubi M, Schertz M, et al. Raw arterial spin labeling data can help identify arterial occlusion in acute ischemic stroke. Stroke, 2015, 46(6): 141-144.
[17]
Tada Y, Satomi J, Abe T, et al. Intra-arterial signal on arterial spin labeling perfusion MRI to identify the presence of acute middle cerebral artery occlusion. Cerebrovascular Dis, 2014, 38(3): 191-196.
[18]
Guo L, Zhang Q, Ding L, et al. Pseudo-continuous arterial spin labeling quantifies cerebral blood flow in patients with acute ischemic stroke and chronic lacunar stroke. Clin Neurol Neurosurg, 2014, 125(10): 229-236.
[19]
Haller S, Zaharchuk G, Thomas DL, et al. Arterial spin labeling perfusion of the brain: emerging clinical applications. Radiology, 2016, 281(2): 337-356.
[20]
Yu S, Liebeskind DS, Dua S, et al. Postischemichyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke. J Cereb Blood Flow Metab, 2015, 35(4):630-637.
[21]
Zaharchuk G. Arterial spin-labeled perfusion imaging in acute ischemic stroke. Stroke, 2014, 45(4): 1202-1207.
[22]
de Havenon A, Haynor DR, Tirschwell DL, et al. Association of collateral blood vessels detected by arterial spin labeling magnetic resonance imaging with neurological outcome after ischemic stroke. JAMA Neurol, 2017, 74(4): 453-458.
[23]
Sugimori H, Fujima N, Suzuki Y, et al. Evaluation of cerebral blood flow using multi-phase pseudo continuous arterial spin labeling at 3-tesla. Magn Reson Imaging, 2015, 33(10): 1338-1344.
[24]
Martin SZ, Madai VI, von Samson-Himmelstjerna FC, et al. 3D GRASE pulsed arterial spin labeling at multiple inflow times in patients with long arterial transit times: comparison with dynamic susceptibility-weighted contrast-enhanced MRI at 3-tesla. J Cereb Blood Flow Metab, 2015, 35(3): 392-401.
[25]
Akiyama T, Morioka T, Shimogawa T, et al. Arterial spin-labeling magnetic resonance perfusion imaging with dual postlabeling delay in internal carotid artery steno-occlusion: validation with digital subtraction angiography. J Stroke Cerebrovasc Dis, 2016, 25(9):2099-2108.
[26]
Lyu J, Ma N, Liebeskind DS, et al. Arterial spin labeling magnetic resonance imaging estimation of antegrade and collateral flow in unilateral middle cerebral artery stenosis. Stroke, 2016, 47(2):428-433.
[27]
Haga S, Morioka T, Shimogawa T, et al. Arterial spin labeling perfusion magnetic resonance image with dual postlabeling delay: A correlative study with acetazolamide loading 123I-iodoamphetamine single-photon emission computed tomography. J Stroke Cerebrovasc Dis, 2016, 25(1): 1-6.
[28]
Goetti R, O Gorman R, Khan N, et al. Arterial spin labelling MRI for assessment of cerebral perfusion in children with moyamoya disease: comparison with dynamic susceptibility contrast MRI. Neuroradiology, 2013, 55(5): 639-647.
[29]
Sugino T, Mikami T, Miyata K, et al. Arterial spin-labeling magnetic resonance imaging after revascularization of moyamoya disease. J Stroke Cerebrovasc Dis, 2013, 22(6): 811-816.
[30]
Zaharchuk G, Do HM, Marks MP, et al. Arterial spin-labeling MRI can identify the presence and intensity of collateral perfusion in patients with moyamoya disease. Stroke, 2011, 42(9): 2485-2491.
[31]
Yun TJ, Paeng JC, Sohn CH, et al. Monitoring cerebrovascular reactivity through the use of arterial spin labeling in patients with moyamoya disease. Radiology, 2016, 278(1): 205-213.
[32]
Wang T, Li Y, Guo X, et al. Reduced perfusion in normal-appearing white matter in mild to moderate hypertension as revealed by 3D pseudocontinuous arterial spin labeling. J Magn Reson Imaging, 2016, 43(3): 635-643.
[33]
Li R, Xiao H, Lyu J, et al. Differential diagnosis of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) and ischemic stroke using 3D pseudocontinuous arterial spin labeling. J Magn Reson Imaging, 2017, 45(1): 199-206.
[34]
Jensen-Kondering U, Lindner T, van Osch MJP, et al. Superselective pseudo-continuous arterial spin labeling angiography. Eur J Radiol, 2015, 84(9): 1758-1767.
[35]
Yu SL, Wang R, Wang R, et al. Accuracy of vessel-encoded pseudocontinuous arterial spin-labeling in identification of feeding arteries in patients with intracranial arteriovenous malformations. AJNR Am J Neuroradiol, 2014, 35(1): 65-71.
[36]
Wakisaka K, Morioka T, Shimogawa T, et al. Epileptic ictal hyperperfusion on arterial spin labeling perfusion and diffusion-weighted magnetic resonance images in posterior reversible encephalopathy syndrome. J Stroke Cerebrovasc Dis, 2016, 25(1):228-237.
[37]
Berry ES, Jezzard P, Okell TW. An optimized encoding scheme for planning vessel-encoded pseudocontinuous arterial spin labeling. Magn Reson Med, 2015, 74(1): 1248-1256.
[38]
Koktzoglou I, Giri S, Piccini D, et al. Arterial spin labeled carotid MR angiography: A phantom study examining the impact of technical and hemodynamic factors. Magn Reson Med, 2016, 75(1):295-301.

PREV Malignant granular cell tumor of the forearm: one case report
NEXT Research progress of functional MRI in irritable bowel syndrome
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn