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The research progress of early diagnose of Alzheimer's disease by resting state functional magnetic resonance
SHE Ying-xia  WANG Shuai-wen  ZHANG Hong-xia  LI Yun-he  GUO Shun-lin 

DOI:10.12015/issn.1674-8034.2018.01.014.


[Abstract] Alzheimer's disease is the most common type of senile dementia. Clinically, AD is mainly characterized by progressive memory loss and cognitive impairment.It has been irreversible when realizing, so early identification and preventing is crucial. In recent years, resting-functional MRI (rs-fMRI) based on blood oxygen level dependent (BOLD) has become a new means to explore the AD brain functional abnormity, a large number of studies have shown that local functional activities and connection anomalies in the associated brain regions of default mode network (DMN) in the AD, this paper reviews the application in the AD brain's function in terms of resting state BOLD-fMRI.
[Keywords] Alzheimer disease；Dementia；Cognition disorders；Magnetic resonance imaging

SHE Ying-xia Department of Radiology, the First Affiliated Hospital of Lanzhou University, Lanzhou 7300000, China

WANG Shuai-wen Department of Radiology, the First Affiliated Hospital of Lanzhou University, Lanzhou 7300000, China

ZHANG Hong-xia Department of Radiology, the First Affiliated Hospital of Lanzhou University, Lanzhou 7300000, China

LI Yun-he Department of Radiology, the First Affiliated Hospital of Lanzhou University, Lanzhou 7300000, China

GUO Shun-lin* Department of Radiology, the First Affiliated Hospital of Lanzhou University, Lanzhou 7300000, China

*Corresponding to: Guo SL, E-mail: guoshunlin@msn.com

Conflicts of interest   None.

Received  2017-05-31
Accepted  2017-10-09
DOI: 10.12015/issn.1674-8034.2018.01.014
DOI:10.12015/issn.1674-8034.2018.01.014.

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