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• Clinical Article •
Study on resting-state functional magnetic resonance imagingin hyperacute phase of mild traumatic brain injury
LU Xing-qi  LI Jie  ZHANG Shu-fei  DING Jian-ping 

DOI:10.12015/issn.1674-8034.2018.02.003.


[Abstract] Objective: To investigate the abnormal changes of brain function in the hyperacute period (<24 h) patients with mild traumatic brain injury (mTBI) by using the amplitude of low-frequency fluctuation (ALFF) in resting state functional magnetic resonance imaging (rs-fMRI).Materials and Methods: 52 mTBI patients (mTBI group) and matched 21 healthy subjects (control group) underwent rs-fMRI examination. The DPARSF software was used to preprocess the fMRI data, the ALFF was compared between the mTBI and control group.Results: Compared with the healthy control group, the mTBI group showed significantly decreasing ALFF values in cerebellum posterior lobe, right middle occipital gyrus and postcentral gyrus. And the ALFF values increased in bilateral frontal lobe, bilateral caudate,medial frontal gyri and insula.Conclusions: In the case of normal routine MRI findings, ALFF technology showed to be more sentitive in detecting rs-fMRI abnormalities in patients with hyperacute mTBI.
[Keywords] Hyperacute period；Craniocerebral trauma；Magnetic resonance imaging, functional；Amplitude of low-frequency fluctuation

LU Xing-qi Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

LI Jie Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

ZHANG Shu-fei South China Normal University, Guangzhou 510631, China

DING Jian-ping* Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

*Corresponding to: Ding JP, E-mail: jpding@vip.sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Hangzhou Key Specialty Disease Specialist Project No. 20150733Q19
Received  2017-11-24
Accepted  2018-01-08
DOI: 10.12015/issn.1674-8034.2018.02.003
DOI:10.12015/issn.1674-8034.2018.02.003.

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