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• Clinical Article •
Study on resting-state functional magnetic resonance imagingin hyperacute phase of mild traumatic brain injury
LU Xing-qi  LI Jie  ZHANG Shu-fei  DING Jian-ping 

DOI:10.12015/issn.1674-8034.2018.02.003.


[Abstract] Objective: To investigate the abnormal changes of brain function in the hyperacute period (<24 h) patients with mild traumatic brain injury (mTBI) by using the amplitude of low-frequency fluctuation (ALFF) in resting state functional magnetic resonance imaging (rs-fMRI).Materials and Methods: 52 mTBI patients (mTBI group) and matched 21 healthy subjects (control group) underwent rs-fMRI examination. The DPARSF software was used to preprocess the fMRI data, the ALFF was compared between the mTBI and control group.Results: Compared with the healthy control group, the mTBI group showed significantly decreasing ALFF values in cerebellum posterior lobe, right middle occipital gyrus and postcentral gyrus. And the ALFF values increased in bilateral frontal lobe, bilateral caudate,medial frontal gyri and insula.Conclusions: In the case of normal routine MRI findings, ALFF technology showed to be more sentitive in detecting rs-fMRI abnormalities in patients with hyperacute mTBI.
[Keywords] Hyperacute period；Craniocerebral trauma；Magnetic resonance imaging, functional；Amplitude of low-frequency fluctuation

LU Xing-qi Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

LI Jie Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

ZHANG Shu-fei South China Normal University, Guangzhou 510631, China

DING Jian-ping* Department of Radiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, China

*Corresponding to: Ding JP, E-mail: jpding@vip.sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Hangzhou Key Specialty Disease Specialist Project No. 20150733Q19
Received  2017-11-24
Accepted  2018-01-08
DOI: 10.12015/issn.1674-8034.2018.02.003
DOI:10.12015/issn.1674-8034.2018.02.003.

[1]
Nathan DE, Oakes TR, Yeh PH, et al. Exploring variations in functional connectivity of the resting statedefault mode network in mild traumatic brain injury. Brain Connect, 2015, 5(2): 102-114.
[2]
Mayer AR, Ling JM, Allen EA, et al. Static and dynamic intrinsic connectivity following mild traumaticbrain injury. J Neurotrauma, 2015, 32(28): 1046-1055.
[3]
Walker KR, Tesco G. Molecular mechanisms of cognitive dysfunction following traumatic brain injury. Front Aging Neurosci, 2013, 5(28): 11744-11754.
[4]
Iraji A, Benson RR, Welch RD, et al. Resting state functional connectivity in mild traumatic brain injury at the acute stage: Indepen-dent component and seed based analyses. Neurotrauma, 2014, 32(14): 1031-1045.
[5]
Johnson B, ZhangK, Gay M, et al. Alteration of brain default network in subacute phase of injury in concussed individuals: resting state fMRI study. Neuroimage, 2012, 59(1): 511-518.
[6]
Xiong KL, Zhang JN, Zhang YL, et al. Brain functional connectivity and cognition in mild traumaticbrain injury. Neuroradiology, 2016, 58(7): 733-739.
[7]
Zhan J, Gao L, Zhou FQ, et al. Amplitude of low-frequency fluctuations in multiple-frequency bands in acute mild traumatic brain injury. Frontiers in Human Neuroscience, 2016, 10(43): 27-36.
[8]
Palacios EM, Sala-Llonch R, Junque C, et al. Resting-state functional magnetic resonance imaging activity and connectivity and cognitive outcome in traumatic brain injury. JAMA Neurol, 2013, 70(7): 845-851.
[9]
Zhou Y, Lui YW, Zuo XN, et al. Characterization of thalamo-cortical association using amplitude and connectivity of functional MRI in mild traumatic brain injury. J Magn Reson Imaging, 2014, 39(6): 1558-1568.
[10]
Yin Y, Li L, Jin C, et al. Abnormal baseline brain activity in posttraumatic stress disorder: a resting-state functional magnetic resonance imaging study. Neuroscience Letters, 2011, 498(3): 185-189.
[11]
Agcaoglu O, Miller R, Mayer AR, et al. Lateralization of resting state networks and relationship to age and gender. Neuroimage, 2015, 104(6): 310-325.
[12]
Mazard A, Laou L, Joliot M, et al. Neural impact of the semantic content of visual mental images and visual percepts. Cogn Brain Res, 2005, 24(3): 423-435.
[13]
Wang K, Jiang T, Yu C, et al. Spontaneous activityassociated with primary visual cortex: a resting-state FMRI study. Cereb Cortex, 2008, 18(3): 697-704.
[14]
Niogi SN, Mukherjee P, Ghajar J, et al. Structural dissociation of attentional control and memory in adults with and without mildtraumatic brain injury. Brain, 2008, 131(12): 3209-3221.
[15]
Zhou Y, Milham MP, Lui YW, et al. Default-mode network disruption in mild traumatic brain injury. Radiology, 2012, 265(3): 882-892.
[16]
Mufson EJ, Mesulam MM. Insula of the old World monkey. II: Afferent cortical input and comments on the claustrum. J Comp Neurol, 1982, 212(1): 23-37.
[17]
Hummer TA, Hulvershorn LA, Karne HS, et al. Emotional response inhibition in bipolar disorder: A functional magnetic resonanceimaging study of traitand state-related abnormalities. Biol Psychiatry, 2013, 73(2): 136-143.
[18]
Chiong W, Wilson SM, D'Esposito M, et al. The salience network causally influences default mode network activity during moral reasoning. Brain, 2013, 136(6): 1929-1941.
[19]
Zhan J, Gao L, Zhou FQ, et al. Decreased regional homogeneity in patients with acute mild traumatic brain injury a resting-state fMRI study. J Nerv Ment Dis, 2015, 203(10): 786-791.
[20]
Wenzel JM, Rauscher NA, Cheer JF, et al. A role for phasic dopamine release within the nucleusaccumbensin encoding aversion: a review of the neurochemical literature. ACS Chem Neurosci, 2015, 6(1): 16-26.
[21]
Lu LY, Cao HL, Wei XE, et al. Iron deposition is positively related to cognitive impairment in patients with chronic mild traumatic brain injury: assessment with susceptibility weighted imaging. Bio Med Research International, 2015, 2015(18): 1-7.

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