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• Clinical Article •
Clinical value of Gd-EOB-DTPA-enhanced MRI for diagnosis of focal hepatic lesions
BAI Xiu-yan  SUN Yu  HOU Jie  ZHANG Nan  MA Xiang-hong  WANG Wei  YANG Ben-qiang 

DOI:10.12015/issn.1674-8034.2018.02.005.


[Abstract] Objective: To evaluate the application value of Gd-EOB-DTPA-enhanced MRI for diagnosing focal hepatic lesions.Materials and Methods: The Gd-EOB-DTPA- enhanced MRI and clinical datas of 34 cases of focal hepatic leisons were enrolled in this study. The pathological results were 20 cases of hepatocellular carcinoma (HCC), 4 cases of intrahepatic cholangiocarcinoma (ICC), 2 cases of combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC), 7 cases of focal nodular hyperplasia (FNH) and 1 case of hepatic angiomyolipoma (HAML). Two radiologists separately analyzed MRI datas in blind way and made pathological diagnosis. Based on postoperative pathological results, diagnosis veracity and consistency of two radiologists were compared.Results: In dynamic contrast phase of Gd-EOB-DTPA enhanced MRI: 5 cases of HCC turned out to be atypical, including 3 cases of mild-enhanced HCC in arterial phase and 2 cases of HCC without obvious washout in transition phase. 1 case of FNH showed a little lower signal intensity than liver parenchyma in transition phase. 2 cases of cHCC-CC both had irregularly dynamic enhancement feature and possessed obvious feeding artery. In hepatobiliary phase: 1 case of HCC showed high signal intensity while the rest HCC were obviously low signal intensity. 4 cases of ICC performed low singal intensity within cloud mild-high signal intensity. 2 cases of cHCC-CC both were low signal intensity within lower signal intensity in the centre. 1 case of FNH featured slightly-low signal intensity within target high signal intensity. The diagnostic accuracy of two radiologists were 94.12% (32/34) and 97.06% (33/34) and the difference had no statistical significance (χ2=0.349, P>0.05). Furthermore, the diagnosis consistency between radiologists was good (kappa=0.945, P<0.05).Conclusions: Gd-EOB-DTPA enhanced MRI may improve the diagnosis veracity of focal hepatic lesion and it has important clinical value.
[Keywords] Gd-EOB-DTPA；Focal hepatic lesion；Hepatobiliary phase；Magnetic resonance imaging

BAI Xiu-yan Department of Radiology, General Hospital of Liaoyang Petrochemical, Liaoyang 111000, China; Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

SUN Yu Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

HOU Jie Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

ZHANG Nan Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

MA Xiang-hong Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

WANG Wei Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

YANG Ben-qiang* Department of Radiology, General Hospital of Shenyang Military Command, Shenyang 110000, China

*Correspondence to: Yang BQ, E-mail: bqyang888@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Project of National Ministry of Industry and Information, National Health and Family Planning Commission of the People’s Republic of China No.2016MDHD11002101
Received  2017-12-03
Accepted  2018-01-05
DOI: 10.12015/issn.1674-8034.2018.02.005
DOI:10.12015/issn.1674-8034.2018.02.005.

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