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Review
Progress of functional MR imaging on the monitoring of therapeutic effects of high-grade gliomas
LIU Ye-qiu  YU Tao 

DOI:10.12015/issn.1674-8034.2018.02.014.


[Abstract] The current management of high-grade gliomas is complicated and changeable. The standard treatment for HGGs is resection and followed by radiotherapy and oral chemotherapy at present. However, the continuous cranial magnetic resonance imaging (MRI) that differentiates treatment response from treatment effect can be challenging and affects clinical decision-making in later stages. A variety of advanced MRI techniques such as diffusion weighted imaging, perfusion weighted imaging, MR spectroscopy, and multiparametric imaging incorporating novel physiologic and biochemical parameters might provide new methods to help characterize tumor progression, pseudoprogression, and pseudo response. In this review, the latest progresses and challenges regarding MR functional imaging in the area of monitoring the efficacy of HGGs are summarized.
[Keywords] Magnetic resonance imaging;Glioma;Diffusion weighted imaging;Diffusion tensor imaging;Perfusion weighted imaging

LIU Ye-qiu Department of Medical Imaging, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, China

YU Tao* Department of Medical Imaging, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, China

*Corresponding to: Yu T, E-mail: yutao@cancerhosp-ln-cmu.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Clinical Capability Construction Project of Liaoning Provincial Hospitals No.LNCCC-B06-2014
Received  2017-11-02
Accepted  2018-01-05
DOI: 10.12015/issn.1674-8034.2018.02.014
DOI:10.12015/issn.1674-8034.2018.02.014.

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