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• Clinical Article •
Feasibility of non-contrast-enhanced magnetic resonance angiography for evaluating portal venous hemodynamics
ZHU Di  ZOU Xian-lun  CHEN Xiao  LU Jing-yu  HU Dao-yu 

DOI:10.12015/issn.1674-8034.2018.03.008.


[Abstract] Objective: To investigate the feasibility of non-contrast-enhanced magnetic resonance angiography (NCE-MRA) using spatial labeling with multiple inversion pulses (SLEEK) in evaluating portal venous hemodynamics.Materials and Methods: Twenty-five patients with portal hypertension were examined with SLEEK-MRA and color Doppler ultrasonography (CDUS) respectively. SLEEK-MRA series were performed with different blood suppression inversion time (BSP TI) settings of 600 ms, 900 ms, 1200 ms and 1500 ms. Portal venous branching grade of SLEEK-MRA series were analyzed with CDUS-measured hemodynamics using Spearman rank correlation coefficient (rs). Patients were divided into 2 groups depending on portal venous velocity and portal venous branching grades as well as BSP TI settings of the 2 groups were compared.Results: At all BSP TI settings, branching grade scores of the left portal vein (LPV) and the right portal vein (RPV) were of statistically significant correlation with CDUS-measured flow velocity of LPV and RPV respectively. The correlation coefficient of LPV at each BSP TI settings (600, 900, 1200, 1500 ms) were 0.534, 0.408, 0.563, 0.621 respectively. The correlation coefficient of RPV at each BSP TI settings were 0.655, 0.578, 0.699, 0.641 respectively. For patients of obviously decreased portal flow velocity, branching grade scores were significantly lower than patients of normal or slightly decreased portal flow velocity. To reach the same portal venous branching visualization, patients of obviously decreased portal flow velocity need to apply with higher BSP TI settings. While most of patients of normal or slightly decreased portal flow velocity applied 900 ms to reach grade 6, 42.9% of patients of obviously decreased portal flow velocity could not reach it even applied a BSP TI setting of 1500ms.Conclusions: SLEEK-MRA has the potential to suggest portal venous flow changes with high-quality morphological visualization of portal vein imaging simultaneously. It is feasible for SLEEK-MRA to provide hemodynamical information.
[Keywords] Hypertension, portal；Portography；Magnetic resonance imaging；Hemodynamics

ZHU Di Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China

ZOU Xian-lun Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China

CHEN Xiao Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China

LU Jing-yu Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China

HU Dao-yu* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, China

*Correspondence to: Hu DY, E-mail: cjr.hudaoyu@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  The project was supported by the National Natural Science Foundation of China No. 81501447, 81571642 the Natural Science Foundation of Hubei Province, China No. 2017CKB900
Received  2017-11-03
Accepted  2017-12-26
DOI: 10.12015/issn.1674-8034.2018.03.008
DOI:10.12015/issn.1674-8034.2018.03.008.

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