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• Clinical Article •
Evaluating hepatic function of hepatic alveolar echinococcosis with magnetic resonance diffusion weighted imaging: initial study
WANG Qi  JANG Yi  Yibanu• ABUDUREHEMAN  LIU Wen-ya 

DOI:10.12015/issn.1674-8034.2018.04.006.


[Abstract] Objective: To evaluate the value of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) for evaluating hepatic function of hepatic alveolar echinococcosis (HAE).Materials and Methods: Retrospective analysis ADC value and DWI imaging of 68 patients and 30 cases of normal people, who underwent routine liver MRI and DWI (b value were 0 and 600 s/mm2). The 68 cases of HAE patients were divided into 3 groups according to Child-Pugh classification criteria, A group has 45 cases, B group has 19 and C group has 4, the ADC value of the adjacent hepatic parenchyma was measured and standardized it with the ADC value of the cerebrospinal fulid at the same spinal cord level, that was ADCratio=ADC/ADCspinal canal. First, the correlation between ADCratio and Child-Pugh score was analyzed. Second, for the control group and case group what were used an independent-samples t test, while for the each case group what were used ANOVA.Results: The control group ADCratio was 0.29±0.03, while the case group ADCratio was 0.26±0.05, respectively, for the more, the ADCratio of group A was 0.27±0.04, the ADCratio of group B was 0.24±0.04 and the group C was 0.21± 0.03. The statistical results showed the ADC value of the case group was moderately correlated with the Child-Pugh score (r=0.432, P<0.01). The control group and case group had significant difference (P<0.01), the ADCratio of the group A, group B and group C also had significant difference (P<0.01), but there was no difference between group B and group C (P>0.05).Conclusions: ADC value could be an indication for evaluating hepatic function for those patients with HAE. With the hepatic function decreasing, the ADC value also decreased.
[Keywords] Echinococcosis, hepatic；Magnetic resonance imaging；Diffusion weighted imaging；Liver function

WANG Qi Department of Imaging Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

JANG Yi Department of Imaging Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

Yibanu• ABUDUREHEMAN Department of Imaging Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

LIU Wen-ya* Department of Imaging Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

*Corresponding to: Liu WY, E-mail: wenyaliu2002@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81460280
Received  2017-10-24
Accepted  2018-03-08
DOI: 10.12015/issn.1674-8034.2018.04.006
DOI:10.12015/issn.1674-8034.2018.04.006.

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