Share：
Share this content in WeChat
X
[Chinese][PDF]108873
• Experience Exchanges •
Imaging manifestation and misdiagnosis analysis of primary angiosarcoma of bone
CHEN Shuo  CHEN Yuan-feng  YUAN Lan  XU Yi-kai  TAN Xiang-liang  CAO Zhen  HUANG De-xiao  TANG Yan-yan  WU Ren-hua 

DOI:10.12015/issn.1674-8034.2018.06.013.


[Abstract] Objective: To explore imaging manifestation of primary angiosarcoma of bone, and to improve the diagnostic accumcy of the disease.Materials and Methods: The imaging materials of 6 patients with primary angiosarcoma of bone proved by pathology were reviewed retrospectively.Results: There were 4 cases who had a single lesion and the other had multiple lesions. Among 4 cases who had a single lesion, 2 cases were located in femur, 1 case in sacroiliac joint and 1 case in vertebral column. The imaging characteristics included the osteolytic destruction and soft tissue swelling or mass, no sclerotic rim, no periosteal proliferation. Had been misdiagnosed as giant cell tumor of bone, fibrous cortical defect of bone, non-ossifying fibroma, tuberculosis, metastatic neoplasm, multiple myeloma before operation.Conclusions: The radiologic appearances of primary angiosarcoma of bone have relative characteristics such as cortical and/or medullary osteolytic destruction, unclear borders, no hardened edge, different degrees of expansion, soft-tissue mass, with minimal periosteums reaction. In addition, multi-center lesions have guiding significance for the diagnosis of this disease.
[Keywords] Hemangiosarcoma；Bone；Radiography；Tomography, X-ray computed；Magnetic resonance imaging

CHEN Shuo Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China; Department of Radiology, Beijing Yanqing District Hospital (Yanqing Hospital of Peking University Third Hospital), Beijing 102100, China

CHEN Yuan-feng Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China

YUAN Lan Medical and Health Analysis Center, Peking University Health Science Center, Beijing 100083, China

XU Yi-kai Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

TAN Xiang-liang Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

CAO Zhen Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China

HUANG De-xiao Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China

TANG Yan-yan Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China

WU Ren-hua* Department of Medical Imaging, the Second Affiliated Hospital, Shantou University Medical College, Shantou 515041, China

*Correspondence to: Wu RH, E-mail: cjr.wurenhua@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Key Research and Development Program of China No.2016YFC0103605
Received  2017-10-17
Accepted  2018-04-23
DOI: 10.12015/issn.1674-8034.2018.06.013
DOI:10.12015/issn.1674-8034.2018.06.013.

[1]
Roessner A, Boehling T. Vascular Tumors//Fletcher CDM, Unni KK, Mertens F. WHO Classification of Tumors. Pathology and Genetics of Tumors of Soft Tissue and Bone. 3rd edition. Lyon: IARC Press, 2002: 322-323.
[2]
Saglik Y, Yildiz Y, Atalar H, et al. Primary angiosarcoma of the fibula: a case report. Acta Orthop Belg, 2007, 73(6): 799-803.
[3]
Verbeke SLJ, Bertoni F, Bacchini P, et al. Distinct histologic features characterize primary angiosarcoma of bone. Histopathology, 2011, 58(2): 254-264.
[4]
Santeusanio G, Bombonati A, Tarantino U, et al. Muhifocal epithelioid angiosarcoma of bone: a potential pitfall in the differential diagnosis with metastatic carcinoma．Appl Immunohistochem. Mol Morphol, 2003, 11(4): 359-363．
[5]
Unni KK, Inwards CY, Bridge JA, et al. Tumors of the bones and joints. AFIP atlas of tumor pathology, 2006, 10(4): 266-273.
[6]
Evans HL, Raymond AK, Ayala AG. Vascular tumors of bone: A study of 17 cases other than ordinary hemangioma, with an evaluation of the relationship of hemangioendothelioma of bone to epithelioid hemangioma, epithelioid hemangioendothelioma, and high-grade angiosarcoma. Hum Pathol, 2003, 34(7): 680-689．
[7]
Wenger DE, Wold LE. Malignant vascular lesions of bone: radiologic and pathologic features．Skeletal Radiol, 2000, 29(11): 619-631．
[8]
杜勇，冯强强，闫东,等.骨的上皮样血管内皮细胞瘤一例.磁共振成像, 2017, 8(3): 233-235.
[9]
胥晓明，蒲学佳，刘宝岳,等.毛细血管扩张型骨肉瘤一例.磁共振成像, 2016, 7(5): 385-387.
[10]
甄俊平，卫小春，王晨,等.骨肉瘤DCE-MRI和瘤组织内乏氧及血管生成相关研究.磁共振成像, 2015, 6(8): 613-617.

PREV Relation between magnetic resonance diffusion-weighted imaging and TOAST classification, traditional risk factors of acute cerebral infarction
NEXT Advanced research of new MRI techniques for bilateral hippocampal and posterior cingulate gyrus injury in type 2 diabetes mellitus
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn