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Advanced research of new MRI techniques for bilateral hippocampal and posterior cingulate gyrus injury in type 2 diabetes mellitus
LIU Nian-jun  LIU Mao-sen  XIN Wen-long  GUO Shun-lin 

DOI:10.12015/issn.1674-8034.2018.06.014.


[Abstract] Type 2 diabetes is a chronic metabolic disease increased by blood glucose, often accompanied with heart, brain, kidney and other organs injury and complications. Long term chronic hyperglycemia can lead to pathophysiological changes in hippocampus and posterior cingulate gyrus in diabetic patients, and damage to the microstructure, leading to cognitive, memory and other brain function disorder. The specific pathogenesis is very complex, the research is still in the exploratory stage. Magnetic resonance imaging technique combined with image, structure and function, can detect early possible pathology, metabolism and physiological functions changes in T2DM of hippocampus and posterior cingulate. It is expected to become an important examination method to explore the pathogenesis of cognitive impairment, quantitative assessment and auxiliary diagnosis.
[Keywords] Diabetes mellitus, type 2；Cognitive impairment；Magnetic resonance imaging；Hippocampus；Damage mechanism

LIU Nian-jun Lanzhou University, Lanzhou 730000, China; Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China

LIU Mao-sen Lanzhou University, Lanzhou 730000, China; Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China

XIN Wen-long Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China

GUO Shun-lin* Department of Radiology, the First Hospital of Lanzhou University, Lanzhou 730000, China

*Corresponding to: Guo SL, E-mail: guoshunlin@msn.com

Conflicts of interest   None.

Received  2017-10-31
Accepted  2018-04-10
DOI: 10.12015/issn.1674-8034.2018.06.014
DOI:10.12015/issn.1674-8034.2018.06.014.

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