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Clinical Article
The clinical application of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) in pancreatic cancer and pancreatitis
TAN Fang-qin  LI Zhen  WANG Qiu-xia  YU Hao  WU Si-si  HU Dao-yu  ZHANG Jie 

DOI:10.12015/issn.1674-8034.2018.09.003.


[Abstract] Objective: To explore the clinical value of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) in pancreatic cancer and pancreatitis.Materials and Methods: A total of 28 pancreatic cancer patients and 21 pancreatitis patients performed conventional full field-of-view (fFOV) and rFOV DWI respectively. Two radiologists assessed image sharpness, distortion, artifacts, lesion conspicuity and overall image quality independently. The objective image quality (IQ) parameters such as contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR) and lesion apparent diffusion coefficient (ADC) were also measured. Quantitative parameters of two different DWI sequences were compared by independent-samples t test.Results: The subjective IQ parameters of rFOV DWI sequence were rated superior to that of fFOV DWI sequence (P<0.001). CNR and SNR were significantly higher in rFOV DWI than in fFOV DWI (P<0.001). There was no significant difference between mean ADC values in rFOV and fFOV DWI sequences [Pancreatic cancer, (1.445±0.292)×10-3 mm2/s vs (1.334±0.235)×10-3 mm2/s, P=0.079; Pancreatitis, (1.448±0.309)×10-3 mm2/s vs (1.441±0.268)×10-3 mm2/s, P=0.910].Conclusions: Compared with fFOV DWI, rFOV DWI has a higher spatial resolution and lesion conspicuity. It also can significantly reduce susceptibility artifacts as well as image distortions.
[Keywords] Reduced field of view;Image quality;Diffusion magnetic resonance imaging;Pancreas

TAN Fang-qin Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

LI Zhen Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

WANG Qiu-xia Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

YU Hao Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

WU Si-si Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

HU Dao-yu Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

ZHANG Jie* Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

*Correspondence to: Zhang J, E-mail: 857382030@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  The project was supported by the National Natural Science Foundation of China No. 81771801 and the Natural Science Foundation of Hubei Province No. 2017CKB900
Received  2018-04-01
Accepted  2018-04-29
DOI: 10.12015/issn.1674-8034.2018.09.003
DOI:10.12015/issn.1674-8034.2018.09.003.

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