Share：
Share this content in WeChat
X
[Chinese][PDF]69969
• Clinical Article •
The value of intravoxel incoherent motion in differentiating hepatic abscess from cystic necrotic malignancy
TAO Feng-ming  LIU Ai-lian  LIU Jing-hong  YANG Wei-ping  WANG Xue-dong 

DOI:10.12015/issn.1674-8034.2018.09.004.


[Abstract] Objective: To explore the value of intravoxel incoherent motion (IVIM) including biexponential models and stretched-exponential models in differential diagnosis of hepatic abscess and cystic necrosis hepatic malignant tumor.Materials and Methods: All patients who performed liver scanning on a 1.5 tesla MR system were retrospectively collected (n=36 patients) in our hospital from September 2015 to October 2017. Seventeen of 36 patients were confirmed as hepatic abscess, the others were confirmed as hepatic malignant tumor. The liver MR protocol included DWI and eDWI. The value of ADC and standard ADC of wall and cavity were calculated and compared between two groups. Then the value of Dmono, D*mono, fmono, Dbi, D*bi, fbi, DDC and α of wall were calculated and compared between two groups. The data were performed by student's t-test to contrast parametric values in two groups, which also obeys normal distribution. The other data were performed by Mann-Whitney test to contrast parametric values in two groups. Diagnostic performance was evaluated with the receiver operating characteristic (ROC) curve analysis.Results: The ADC value and standard ADC value of cavity and wall, fmono value and Dbi value of wall, the DDC value of wall kept statistically significant (P<0.05). The area under the ROC curve of cavity of ADC and standard ADC were respectively 0.897 and 0.764. The area under the ROC curve of wall of ADC and standard ADC were respectively 0.811 and 0.753. The area under the ROC curve of wall of fmono, Dbi and DDC were respectively 0.789, 0.703 and 0.881.Conclusions: The standard ADC and ADC value of wall and cavity, fmono, Dbi and DDC value of wall have stastically significance and may be helpful for differentiating pyogenic hepatic abscesses and cystic necrotic hepatic malignant tumor.
[Keywords] Liver abscess；Liver neoplasms；Magnetic resonance imaging；Diagnosis, differential

TAO Feng-ming Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Ai-lian* Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Jing-hong Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

YANG Wei-ping Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

WANG Xue-dong Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

*Correspondence to: Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2018-04-09
Accepted  2018-05-14
DOI: 10.12015/issn.1674-8034.2018.09.004
DOI:10.12015/issn.1674-8034.2018.09.004.

[1]
Parsai A, Zerizer I, Roche O, et al. Assessment of diffusion-weighted imaging for characterizing focal liver lesions. Clin Imaging, 2015, 39(2): 278-284.
[2]
Woo S, Lee JM, Yoon JH, et al. Intravoxel incoherent motion diffusion-weighted MR imaging of hepatocellular carcinoma: correlation with enhancement degree and histologic grade. Radiology, 2014, 270(3): 758-767.
[3]
Luo M, Zhang L, Jiang XH, et al. Intravoxel incoherent motion diffusion-weighted imaging: evaluation of the differentiation of solid hepatic lesions. Transl Oncol, 2017, 10(5): 831-838.
[4]
Liu L, Chen W, Lu X, et al. Pyogenic liver abscess: a retrospective study of 105 cases in an emergency department from east China. J Emerg Med, 2017, 52(4): 409-416.
[5]
何瑜，贺国庆，张顺源. CT动态增强与MRI在肝脓肿病理分期中的诊断及临床价值．中国CT和MRI杂志, 2016, 14(6): 60-63.
[6]
Chen SC, Huang CC, Tsai SJ, et al. Severity of disease as main predictor for mortality in patients with pyogenic liver abscess. Am J Surg, 2009, 198(2): 164-172.
[7]
陈银葵，邓欢，蔡思娜，等．肿瘤晚期患者感染与肿瘤热早期诊断的临床研究．中华医院感染学杂志, 2016, 26(12): 2721-2723.
[8]
Yi L, Lihua Q, Xianming D, et al. Hepatic metastasis complicated by abscess formation. Pak J Med Sci, 2015, 31(4): 1015-1017.
[9]
Park HJ, Kim SH, Jang KM, et al. Differentiating hepatic abscess from malignant mimickers: value of diffusion-weighted imaging with an emphasis on the periphery of the lesion. J Magn Reson Imaging, 2013, 38(6): 1333-1341.
[10]
Balci NC, Semelka RC, Noone TC, et al. Pyogenic hepatic abscesses: MRI findings on T1- and T2-weighted and serial gadolinium-enhanced gradient-echo images. J Magn Reson Imaging, 1999, 9(2): 285-290.
[11]
Luo M, Zhang L, Jiang XH, et al. Intravoxel incoherent motion: application in differentiation of hepatocellular carcinoma and focal nodular hyperplasia. Diagn Interv Radiol, 2017, 23(4): 263-271.
[12]
Cohen AD, Schieke MC, Hohenwalter MD, et al. The effect of low b-values on the intravoxel incoherent motion derived pseudodiffusion parameter in liver. Magn Reson Med, 2015, 73(1): 306-311.
[13]
Zhang SX, Jia QJ, Zhang ZP, et al.Intravoxel incoherent motion MRI: emerging applications for nasopharyngeal carcinoma at the primary site. Eur Radiol, 2014, 24(8): 1998-2004.
[14]
Dijkstra H, Baron P, Kappert P, et al. Effects of microperfusion in hepatic diffusion weighted imaging. Eur Radiol, 2012, 22(4): 891-899.
[15]
Liu XH, Zhou LP, Peng WJ, et al. Comparison of stretched-Exponential and monoexponential model diffusion-Weighted imaging in prostate cancer and normal tissues. J Magn Reson Imaging, 2015, 42(4): 1078-1085.
[16]
Bai Y, Lin Y, Tian J, et al. Grading of gliomas by using monoexponential, biexponential, and stretched exponential diffusion-weighted MR imaging and diffusion kurtosis MR imaging. Radiology, 2016, 278(2): 496-504.
[17]
Kevin MB, Kathleen MS, Raoqiong B, et al. Characterization of continuously distributed cortical water diffusion rates with a stretched-exponential model. Magn Reson Med, 2003, 50(4): 727-734.

PREV The clinical application of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) in pancreatic cancer and pancreatitis
NEXT Study of DCE-MRI and IVIM-DWI on degenerative intervertebral disc neovascularization in patients with low back pain
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn