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• Clinical Article •
The value of intravoxel incoherent motion in differentiating hepatic abscess from cystic necrotic malignancy
TAO Feng-ming  LIU Ai-lian  LIU Jing-hong  YANG Wei-ping  WANG Xue-dong 

DOI:10.12015/issn.1674-8034.2018.09.004.


[Abstract] Objective: To explore the value of intravoxel incoherent motion (IVIM) including biexponential models and stretched-exponential models in differential diagnosis of hepatic abscess and cystic necrosis hepatic malignant tumor.Materials and Methods: All patients who performed liver scanning on a 1.5 tesla MR system were retrospectively collected (n=36 patients) in our hospital from September 2015 to October 2017. Seventeen of 36 patients were confirmed as hepatic abscess, the others were confirmed as hepatic malignant tumor. The liver MR protocol included DWI and eDWI. The value of ADC and standard ADC of wall and cavity were calculated and compared between two groups. Then the value of Dmono, D*mono, fmono, Dbi, D*bi, fbi, DDC and α of wall were calculated and compared between two groups. The data were performed by student's t-test to contrast parametric values in two groups, which also obeys normal distribution. The other data were performed by Mann-Whitney test to contrast parametric values in two groups. Diagnostic performance was evaluated with the receiver operating characteristic (ROC) curve analysis.Results: The ADC value and standard ADC value of cavity and wall, fmono value and Dbi value of wall, the DDC value of wall kept statistically significant (P<0.05). The area under the ROC curve of cavity of ADC and standard ADC were respectively 0.897 and 0.764. The area under the ROC curve of wall of ADC and standard ADC were respectively 0.811 and 0.753. The area under the ROC curve of wall of fmono, Dbi and DDC were respectively 0.789, 0.703 and 0.881.Conclusions: The standard ADC and ADC value of wall and cavity, fmono, Dbi and DDC value of wall have stastically significance and may be helpful for differentiating pyogenic hepatic abscesses and cystic necrotic hepatic malignant tumor.
[Keywords] Liver abscess；Liver neoplasms；Magnetic resonance imaging；Diagnosis, differential

TAO Feng-ming Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Ai-lian* Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

LIU Jing-hong Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

YANG Wei-ping Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

WANG Xue-dong Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

*Correspondence to: Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2018-04-09
Accepted  2018-05-14
DOI: 10.12015/issn.1674-8034.2018.09.004
DOI:10.12015/issn.1674-8034.2018.09.004.

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