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Research on clinical application value of MRI PWI technology evaluating brain blood state in severe brain injury with hyperbaric oxygen intervention
CAI Jun  CHEN Bo  WANG Cai-hong  FANG Wei  SHEN Jun-kang 

DOI:10.12015/issn.1674-8034.2018.09.008.


[Abstract] Objective: The aim of the current study is to explore the clinical application value of magnetic resonance imaging perfusion weighted imaging (PWI) technology evaluating brain blood state in traumatic brain injury (TBI) with hyperbaric oxygen (HBO) intervention.Materials and Methods: We selected 20 patients with severe brain injury who were then devided into hyperbaric oxygen therapy group and nonhyperbaric oxygen therapy group. Compared the difference of the cerebral blood flow (CBF) and the cerebral blood volume (CBV) on MRI PWI between the two groups in time intervals. Evaluated the therapeutic effect of hyperbaric oxygen intervention in severe brain injury according to CBF and CBV, and then predicting TBI prognosis.Results: The CBF and CBV values of the PWI images in HBO group were significantly better than control group, the difference was statistically significant (P<0.05).Conclusions: Severe brain injury with hyperbaric oxygen intervention has a stimulative effect on the recovery of brain injury, recanalization of local blood flow, and recovery of blood volume. MRI PWI technology has high clinical application value in severe brain injury with HBO intervention.
[Keywords] Brain injuries；Hyperbaric oxygenation；Perfusion imaging；Magnetic resonance imaging

CAI Jun Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

CHEN Bo* Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

WANG Cai-hong Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

FANG Wei Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

SHEN Jun-kang Department of Radiology, The Affiliated Second Hospital to Suzhou University, Suzhou, 215000, China

*Correspondence to: Chen Bo, E-mail: 21984699@qq.com

Conflicts of interest   None.

Received  2018-05-10
Accepted  2018-07-28
DOI: 10.12015/issn.1674-8034.2018.09.008
DOI:10.12015/issn.1674-8034.2018.09.008.

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