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Research on clinical application value of MRI PWI technology evaluating brain blood state in severe brain injury with hyperbaric oxygen intervention
CAI Jun  CHEN Bo  WANG Cai-hong  FANG Wei  SHEN Jun-kang 

DOI:10.12015/issn.1674-8034.2018.09.008.


[Abstract] Objective: The aim of the current study is to explore the clinical application value of magnetic resonance imaging perfusion weighted imaging (PWI) technology evaluating brain blood state in traumatic brain injury (TBI) with hyperbaric oxygen (HBO) intervention.Materials and Methods: We selected 20 patients with severe brain injury who were then devided into hyperbaric oxygen therapy group and nonhyperbaric oxygen therapy group. Compared the difference of the cerebral blood flow (CBF) and the cerebral blood volume (CBV) on MRI PWI between the two groups in time intervals. Evaluated the therapeutic effect of hyperbaric oxygen intervention in severe brain injury according to CBF and CBV, and then predicting TBI prognosis.Results: The CBF and CBV values of the PWI images in HBO group were significantly better than control group, the difference was statistically significant (P<0.05).Conclusions: Severe brain injury with hyperbaric oxygen intervention has a stimulative effect on the recovery of brain injury, recanalization of local blood flow, and recovery of blood volume. MRI PWI technology has high clinical application value in severe brain injury with HBO intervention.
[Keywords] Brain injuries；Hyperbaric oxygenation；Perfusion imaging；Magnetic resonance imaging

CAI Jun Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

CHEN Bo* Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

WANG Cai-hong Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

FANG Wei Department of Radiology, Taicang City First People's Hospital Affiliated to Suzhou University, Suzhou, 215400, China

SHEN Jun-kang Department of Radiology, The Affiliated Second Hospital to Suzhou University, Suzhou, 215000, China

*Correspondence to: Chen Bo, E-mail: 21984699@qq.com

Conflicts of interest   None.

Received  2018-05-10
Accepted  2018-07-28
DOI: 10.12015/issn.1674-8034.2018.09.008
DOI:10.12015/issn.1674-8034.2018.09.008.

[1]
Margulies S, Anderson G, Atif F, et al. Combination therapies for traumatic brain injury: retrospective considerations. J Neurotrauma, 2016, 33(1): 101-112.
[2]
Zanier ER, Marchesi F, Ortolano F, et al. Fractalkine receptor deficiency is associated with early protection but late worsening of outcome following brain trauma in mice. J Neurotrauma, 2016, 33(11): 1060-1072.
[3]
沈天真，陈星荣．神经影像学．上海：上海科学技术出版社, 2004: 554-557.
[4]
Hiler M, Czosnyka M, Hutchinson P, et a1. Predictive value of in—itial computerized tomography sean，intracranial pressure，and state of autoregulation in patients with traumatic brain injury. J Neurosurg, 2006, 104(5): 731-737.
[5]
Chieregato A, Tanfani A, Compagnone C, et a1. Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral pedusion pressure. Neurosurg, 2007, 60(1): 115-123.
[6]
王培东．临床高压氧医学与脑复苏新进展．香港：世界医学出版社, 2000: 41.
[7]
Zhou BC, Liu LJ, Liu B. Neuroprotection of hyperbaric oxygen therapy in sub-acute traumatic brain injury: not by immediately improving cerebral oxygen saturation and oxygen partial pressure. Neural Regen Res, 2016, 11(9): 1445-1449.
[8]
Geng F, Ma Y, Xing T, et al. Effects of hyperbaric oxygen therapy on inflammasome signaling after traumatic brain injury. Neuroimmunomodulation, 2016, 23(2):122-129.
[9]
Huang L, Obenaus A, Hamer M, et al. Neuroprotective effect of hyperbaric oxygen therapy in a juvenile rat model of repetitive mild traumatic brain injury. Med Gas Res, 2016, 6(4):187-193.
[10]
Figueroa XA, Wright JK. Hyperbaric oxygen: B-level evidence in mild traumatic brain injury clinical trials. Neurology, 2016, 87(13):1400-1406.
[11]
Churchill S, Miller RS, Deru K, et al. Simple and procedural reaction time for mild traumatic brain injury in a hyperbaric oxygen clinical trial. Mil Med, 2016, 181(5S): 40-44.
[12]
Niogi SN, Mukherjee P, Ghajar J, et a1. Extent of microstructural white matter injury in postconcussive sydrome correlates with impaired eongenitive reaction time: a 3T diffusion tensor imaging study of mild traumatic brain iajury. AJNR Am J Neuroradio, 2008, 29(5): 967-973.
[13]
Akpinar E, Koroglu M, Ptak T, et a1. Diffusion tensor MR imaging in pediatric head trauma. J Comput Assist Tomogr, 2007, 31(5): 657-661.
[14]
Inglese M, Makani S, Johnson G, et a1. Diffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study. J Neurosurg, 2005, 103(2): 298-303.
[15]
陈宁，刘文，李慧国，等．持续性植物状态的磁共振与扩散张量成像．中国医学影像技术, 2003, 19(11): 1442-1444.
[16]
郛兴华，刘启旺，郑国芳，等．扩散加权成像在超早期脑梗死诊断中的应用．中国医学影像技术, 2003, 19(7): 855-856.

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