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Clinical research of voxel-based morphometry (VBM) in ophthalmology
LIU Yu-xin  YE Lei  SHAO Yi 

Co-first Author: YE Lei DOI:10.12015/issn.1674-8034.2018.09.010.


[Abstract] With the rapid development of medical imaging technology and increasing requirement of clinical ophthalmic diagnosis, the magnetic resonance imaging (MRI) technology has been widely used in the diagnosis, treatment and the prognostic evaluation of ophthalmic diseases. The voxel-based morphometry (VBM) analyzed the changes in the cerebral gray and white matter density or volume of each voxel in MRI by quantitative calculation, reflecting the difference of the corresponding anatomical structure. In addition, VBM, as a new magnetic resonance imaging technology, has been widely used in the research of clinical ophthalmic diseases in recent years, which provides a powerful tool for elucidating the pathological mechanism and monitoring the course of disease. This paper will briefly review the clinical application of VBM in ophthalmological diseases.
[Keywords] Eye diseases；Gray matter；White matter；Anthropometry；Magnetic resonance imaging

LIU Yu-xin Department of Ophthalmology, The First Affiliated Hospitalof Nanchang University, Nanchang 330006, China

YE Lei Department of Ophthalmology, The First Affiliated Hospitalof Nanchang University, Nanchang 330006, China

SHAO Yi* Department of Ophthalmology, The First Affiliated Hospitalof Nanchang University, Nanchang 330006, China

*Corresponding to: Shao Y, E-mail: freebee99@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Funding from the National Natural Science Foundation No. 81160118, 81460092, 81400372, 81660158 Long Voyage Project in Jiangxi No. 2014022 Major Projects of Jiangxi Natural Science Foundation No. 2016ACB21017 Jiangxi Natural Science Foundation No. 20151BAB215016 Key Research and Development Projects in Jiangxi No. 20151BBG70223
Received  2018-05-03
Accepted  2018-07-21
DOI: 10.12015/issn.1674-8034.2018.09.010
Co-first Author: YE Lei DOI:10.12015/issn.1674-8034.2018.09.010.

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