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Image evaluation of skeletal muscle fat quantification and its clinical value in type 2 diabetes mellitus
YU Fu-yao  SUN He  MENG Yan  PAN Shi-nong 

DOI:10.12015/issn.1674-8034.2018.11.013.


[Abstract] In recent years, with the advancement of imaging technology, the determination of skeletal muscle fat content has become increasingly accurate. Body fat is considered to be a main target organ of insulin, and body fat composition is closely associated with insulin resistance. In particular, ectopic deposition and abnormal metabolism of skeletal muscle fat are one of the important factors in the pathogenesis of insulin resistance. Type 2 diabetes is one of the most common non-communicable diseases in the world with alarmingly high incidence globally, especially in developing countries. At present, insulin resistance (IR) is considered to be the main pathogenesis of type 2 diabetes. Therefore, the clinical value of the correlation between skeletal muscle fat content and insulin resistance is particularly critical. Image evaluation of skeletal muscle fat content and the study of its association with insulin resistance play a crucial role in the management and treatment of diabetes such as physical activity, life style modification, and medication.
[Keywords] Fats；Muscles；Diabetes mellitus, type 2；Insulin resistance；Diagnostic imaging

YU Fu-yao Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

SUN He Department of Radiology, Fourth Affiliated Hospital of China Medical University, Shenyang 110004, China

MENG Yan Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

PAN Shi-nong* Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China

*Corresponding to: Pan SN, E-mail: cjr.panshinong@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of the National Key R & D Plan and Special Research and Development Program of Digital Diagnosis and Treatment Equipment No. 2016YFC0107102
Received  2018-04-11
DOI: 10.12015/issn.1674-8034.2018.11.013
DOI:10.12015/issn.1674-8034.2018.11.013.

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