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• Clinical Article •
The value of DWI combined with minimum ADC value in differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma and meningioma
LIANG Xiaohong  ZHOU Qing  ZHAO Zhiyong  KE Xiaoai  HAN Lei  ZHOU Junlin 

Cite this article as: Liang XH, Zhou Q, Zhao ZY, et al. The value of DWI combined with minimum ADC value in differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma and meningioma. Chin J Magn Reson Imaging, 2019, 10(1): 8-13. DOI:10.12015/issn.1674-8034.2019.01.002.


[Abstract] Objective: Differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma (SFT/HPC) and meningioma by diffusion weighted imaging (DWI) combined with minimum apparent diffusion coefficient (MinADC) to improve preoperative diagnostic accuracy.Materials and Methods: Retrospective analysis of preoperative clinical data, DWI characteristics and pathological data of 10 patients with SFT/HPC (WHO Ⅱ grade) and 22 patients with meningioma (WHO Ⅱ grade) confirmed by surgery and pathology from March 2012 to August 2018. MinADC value of the SFT/HPCs (n=10) was measured on ADC map and was compared with that of meningiomas (n=22). Comparison of MinADC values between SFT/HPC and meningioma was conducted by Welch test. Using the receiver operating characteristic curve (ROC curve) to evaluate the differential diagnosis value of MinADC value.Results: In 10 cases of SFT/HPC, the solid components of the tumor showed equal signal (n=8) and slightly higher signal (n=2) on DWI, the mean value of MinADC was (1.16±0.23)×10-3 mm2/s. In 22 cases of meningioma, the solid components of the tumor showed slightly higher signal (n=18) and equal signal (n=2) and high signal (n=2) on DWI, the mean value of MinADC was (0.80±0.12)×10-3 mm2/s, less than that of SFT/HPC, the difference of MinADC values between the two groups was statistically significant (P<0.01). For the differentiation between SFT/HPC and meningioma, the critical cutoff MinADC value was 0.90×10-3 mm2/s, which provided the best combination of sensitivity (97.6%) and specificity (94.3%), the area under the ROC curve was 0.92±0.32, corresponding to histopathological findings, the Kappa value of the repeat measurements was 0.91 for SFT/HPC and 0.87 for meningioma, which indicated a good concordance of the results.Conclusions: MinADC value can be used as a quantitative tool to distinguish intracranial SFT/HPC from meningioma and improve the accuracy of preoperative diagnosis.
[Keywords] brain neoplasms；solitary fibrous tumors；hemangiopericytoma；magnetic resonance imaging

LIANG Xiaohong Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

ZHOU Qing Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

ZHAO Zhiyong Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

KE Xiaoai Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

HAN Lei Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

ZHOU Junlin* Radiology Imaging Center, Second Hospital of Lanzhou University, Lanzhou 730030, China

*Correspondence to: Zhou JL, E-mail: LZUzjl601@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article was funded by the Gansu Provincial Health Industry Research Project No. GSWSKY2016-06 Internal Project of the Second Hospital of Lanzhou University (doctoral reserch fund) No. 2015-1-04
Received  2018-07-12
Accepted  2018-11-20
DOI: 10.12015/issn.1674-8034.2019.01.002
Cite this article as: Liang XH, Zhou Q, Zhao ZY, et al. The value of DWI combined with minimum ADC value in differential diagnosis of intracranial solitary fibrous tumor/hemangiopericytoma and meningioma. Chin J Magn Reson Imaging, 2019, 10(1): 8-13. DOI:10.12015/issn.1674-8034.2019.01.002.

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