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• Clinical Article •
Analysis of magnetic resonance imaging findings and clinicopathologic features of sacral Schwannoma
FANG Hanzhen  HU Meiyu  PAN Bitao  Pan Ximin  LAI Yingrong  JIANG Bo 

Cite this article as: Fang HZ, Hu MY, Pan BT, et al. Analysis of magnetic resonance imaging findings and clinicopathologic features of sacral Schwannoma. Chin J Magn Reson Imaging, 2019, 10(1): 42-47. DOI:10.12015/issn.1674-8034.2019.01.008.


[Abstract] Objective: To assess the invasive feature and characteristic MRI manefistations of sacral schwannoma.Materials and Methods: The maximal dimension of tumoral mass (MDTS) was measured in the 26 patients with sacral schwannoma, who were typed and grouped based on tumoral site and invasive extent, presences of tumoral cystic degeneration and "pod-like margin" sign. The difference s of MDTS between types and between groups were compared. The signal appearances on T2-weighted image and post-contrast enhancement pattern were observed of the tumoral parenchyma, and correlated to histologic findings of HE stain.Results: The 26 patients included 4 cases of type 1, 5 of type 2, 10 of type 3, and 7 of type 4. The incidence of pre-sacral soft tissue mass surpassed that of post-laminal region (χ2=13.066, P=0.011). Osteolysis was revealed in midline sacrum in 5 patients and in para-midline sacrum in 14 patients. The MDTS of type 3 was larger than that of rest types (t=2.655, P=0.014). The MDTS of 8 cases of GISS exceeded that of 18 cases of non-GISS (t=-3.027, P=0.006). No significant difference was shown between the 12 patients with "pod-like margin" sign and the 14 patients without the sign (t=1.896, P=0.07). Both MDTS and duration in 12 patients with cystic degeneration exceeded those in 14 with no cystic degeneration (t=2.928, P=0.007. t=-2.187, P=0.039. Respectively). Region Ⅰ was demonstrated with mild hyperintensity on T2-weighted image, marked enhancement and correlated to the area of Atoni A, while region Ⅱ was noted with hyperintensity on T2-weighted image, mild or no enhancement and correlated to the area of Atoni B.Conclusions: Sacral schwannoma possesses the features of eccentric osteolysis and pre-sacral infiltration. The mild and marked hyperintensities on T2-weighted image, and the intrinsic post-contrast enhancement discrepancy comprise the characteristics of MRI appearances of this tumor.
[Keywords] neurilemmoma；sacrum；magnetic resonance imaging

FANG Hanzhen Department of Radiology, Huilai County People's Hospital, Jieyang 515200, China

HU Meiyu Department of Radiology, Sun Yat Sen University Sixth Affiliated Hospital, Guangzhou 510700, China

PAN Bitao Department of Clinical Diagnostic Radiology, Sun Yat Sen University First Affiliated Hospital, Guangzhou 510080, China

Pan Ximin Department of Radiology, Sun Yat Sen University Sixth Affiliated Hospital, Guangzhou 510700, China

LAI Yingrong Department of Pathology, Sun Yat Sen University First Affiliated Hospital, Guangzhou 510080, China

JIANG Bo* Department of Clinical Diagnostic Radiology, Sun Yat Sen University First Affiliated Hospital, Guangzhou 510080, China

*Correspondence to: Jiang B, E-mail: csujbo@163.com

Conflicts of interest   None.

Received  2018-06-30
Accepted  2018-11-20
DOI: 10.12015/issn.1674-8034.2019.01.008
Cite this article as: Fang HZ, Hu MY, Pan BT, et al. Analysis of magnetic resonance imaging findings and clinicopathologic features of sacral Schwannoma. Chin J Magn Reson Imaging, 2019, 10(1): 42-47. DOI:10.12015/issn.1674-8034.2019.01.008.

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