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• Clinical Article •
Value of different 3.0 T MRI sequences in diagnosis of subtype of renal cell carcinoma
MENG Qingcheng  XIA Weili  YAN Liangliang  LI Hailiang  QU Jinrong  ZHAO Erjiang 

Cite this article as: Meng QC, Xia WL, Yan LL, et al. Value of different 3.0 T MRI sequences in diagnosis of subtype of renal cell carcinoma. Chin J Magn Reson Imaging, 2019, 10(2): 140-144. DOI:10.12015/issn.1674-8034.2019.02.013.


[Abstract] Objective: To explore the clinical value of different MRI sequences in differenting the subtype of renal cell carcinoma, and to provide the imaging basis of making treatment plan and determining the prognosis of renal cell carcinoma.Materials and Methods: The clinical data of forty renal cell carcinoma patients proved by post-operation pathology were analyzed retrospectively in our hospital from March of 2014 to March of 2017, which were grouped as clear cell renal carcinoma group (21 cases) and no clear cell renal carcinoma group (19 cases, in which papillary cell type 11 cases, chromophobe cell type 8 cases). All the patients were checked with abdominal 3.0 T MRI and the sequences including routine scan, diffusion-weighted imaging and dynamic contrast enhancement. The occurrence rates of cystic degeneration, hemorrhage, necrosis and vein tumor emboli were statistical analysis, and the difference of apparent diffusion coefficient (ADC) value and tumor-cortical augmentation index in different time were also measured between two groups.Results: Compared with no clear cell renal carcinoma group, the occurrence rates of necrosis and cystic degeneration in clear cell renal carcinoma group were high, and the occurrence rates of hemorrhage were low, all which had significant difference (χ2=17.378, 5.414, 4.043, P=0.00, 0.020, 0.044), but the occurrence rate of vein tumor emboli between two groups was not significantly different (χ2=1.380, P=0.240). Area under the curve (AUC) of hemorrhage, necrosis, cystic degeneration and vein tumor emboli were 0.663, 0.828, 0.680 and 0.585; the ADC value of clear cell renal carcinoma was higher than that of no clear cell renal carcinoma, which was different significantly [(2.01±0.33)×10-3 mm2/s vs (1.49±0.13)×10-3 mm2/s, t=6.269, P=0.00]; the tumor-cortical augmentation index of clear cell renal carcinoma group in different stages were higher than those of no clear cell renal carcinoma (t=4.082, 6.059, 6.083, P=0.00, 0.00, 0.00), and the AUCs of tumor-cortical augmentation index in different phases were 0.817, 0.929 and 0.897 separately. The ADC values plus tumor-cortical augmentation index in nephrographic phase was 0.976, and the sensitivity was 0.976, specificity was 1.00.Conclusions: The sensitivity and specificity of ADC values plus tumor-cortical augmentation index were the highest in different 3.0 T MRI sequences, which had clinical reference value definitely.
[Keywords] renal cell carcinoma, subtype；magnetic resonce imaging；apparent diffusion coefficient

MENG Qingcheng Department of Radiology, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

XIA Weili Department of Radiology, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

YAN Liangliang Department of Radiology, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

LI Hailiang* Department of Radiology, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

QU Jinrong Department of Radiology, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

ZHAO Erjiang Department of Medical Records Room, Henan Tumor Hospital/Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou 450008, China

*Correspondence to: Li HL, E-mail: Cjr.lihailiang@vip.163.com

Conflicts of interest   None.

Received  2018-05-27
Accepted  2018-09-21
DOI: 10.12015/issn.1674-8034.2019.02.013
Cite this article as: Meng QC, Xia WL, Yan LL, et al. Value of different 3.0 T MRI sequences in diagnosis of subtype of renal cell carcinoma. Chin J Magn Reson Imaging, 2019, 10(2): 140-144. DOI:10.12015/issn.1674-8034.2019.02.013.

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