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• Clinical Article •
Evaluation of the relations between middle cerebral artery plaque characteristics and ischemic stroke and transient ischemic attack: three-dimensional high-resolution magnetic resonance imaging
WANG Yan  BAI Yan  WANG Zhixue  MA Xiaoyue  WEI Wei  SHI Shaojie  WANG Meiyun 

Cite this article as: Wang Y, Bai Y, Wang ZX, et al. Evaluation of the relations between middle cerebral artery plaque characteristics and ischemic stroke and transient ischemic attack: three-dimensional high-resolution magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(3): 169-173. DOI:10.12015/issn.1674-8034.2019.03.002.


[Abstract] Objective: To analyze the relations between middle cerebral artery plaque characteristics and ischemic stroke and transient ischemic attack by 3D turbo spin echo sequence.Materials and Methods: A retrospective analysis was performed on 58 patients with middle cerebral artery stenosis. All patients underwent routine MRI and pre- and post-contrast 3D turbo spin echo sequence (3D-SPACE) images at 3.0 T MRI. Patients were divided into ischemic stroke group and transient ischemic attack group according to the high signal in the blood supply area of middle cerebral artery on diffusion-weighted imaging. The stenosis rate, eccentricity index, degree of plaque enhancement and remodeling index were quantitatively analyzed, and the degree of plaque enhancement and remodeling were qualitatively measured. Analyzed the relations between middle cerebral artery plaque characteristics and ischemic stroke and transient ischemic attack.Results: Twenty-two ischemic stroke and 36 transient ischemic attack were analyzed. The eccentricity index and remodeling index of ischemic stroke were significantly higher than those in transient ischemic attack (eccentricity index: 0.701±0.099 vs. 0.559±0.208, P=0.001; remodeling index: 0.922±0.194 vs. 0.761±0.182, P=0.003; contrast enhancement: 131±44 vs. 94±38, P=0.002). There was no statistically significant difference in stenosis rate between the two groups.Conclusions: The characteristics of middle cerebral artery plaque detected by 3D turbo spin echo sequence can effectively predict the occurrence of stroke.
[Keywords] intracranial thrombosis；brain ischemia；plaque, atherosclerotic；middle cerebral artery；magnetic resonance imaging

WANG Yan Department of Radiology, the First Affiliated Hospital of Henan University, Kaifeng 475000, China

BAI Yan Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China; Henan Key Laboratory for Medical Imaging of Neurological Disease, Zhengzhou 450003, China

WANG Zhixue Department of Radiology, the First Affiliated Hospital of Henan University, Kaifeng 475000, China

MA Xiaoyue Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

WEI Wei Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

SHI Shaojie Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China

WANG Meiyun* Department of Radiology, Henan Provincial People's Hospital, Zhengzhou 450003, China; Henan Key Laboratory for Medical Imaging of Neurological Disease, Zhengzhou 450003, China

*Correspondence to: Wang MY, E-mail: marian9999@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  Supported by National Key Research and Development Program No. 2017YFE0103600 National Natural Science Foundation No. 81720108021、81641168 Henan Province Scientific and Technological Open and Cooperating Project No. 152106000014 Henan Province Medical Scientific and Technological Research Project No. 201501011
Received  2018-08-31
Accepted  2018-10-28
DOI: 10.12015/issn.1674-8034.2019.03.002
Cite this article as: Wang Y, Bai Y, Wang ZX, et al. Evaluation of the relations between middle cerebral artery plaque characteristics and ischemic stroke and transient ischemic attack: three-dimensional high-resolution magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(3): 169-173. DOI:10.12015/issn.1674-8034.2019.03.002.

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