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• Clinical Article •
Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma
DANG Baohua  ZHAO Xin  ZHANG Xiaoan 

Cite this article as: Dang BH, Zhao X, Zhang XA. Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma. Chin J Magn Reson Imaging, 2019, 10(3): 195-200. DOI:10.12015/issn.1674-8034.2019.03.007.


[Abstract] Objective: To retrospectively evaluate dynamic contrast-enhanced MR imaging (DCE-MRI) for differentiating postobstructive pneumonitis and atelectasis from centrally located lung carcinomas, and to compare it with common MRI sequences and CT.Materials and Methods: Forty-four consecutive patients with central lung carcinoma proved pathologically between March 2017 to January 2018 were analyzed. All the patients underwent 3.0 T DCE-MRI, common MRI sequences and CT before treatment. MRI scan sequences were as followed, T1WI, T2WI, DWI and DCE-MRI. The detectability of different examines and sequences were statistically compared using χ2 test. The differences of signal intensity on DWI and ADC value between lung carcinomas and postobstructive pneumonitis and atelectasis were statistically compared using t test.Results: The detectability of CT, T1WI、T2WI、T2WI+DWI、DCE-MRI、T2WI+DWI+DCE-MRI was statistically different (χ2=74.756, P=0.000). The detectability of DCE-MRI was the same as T2WI combined DWI (75.0%, 33/44), and higher than T1WI (13.6%, 6/44), T2WI (50.0%, 22/44) or CT alone (40.9%, 18/44), and the differences were statistically significant (χ2=33.570, 5.867, 10.493, respectively, P<0.05). However, DCE-MRI can show the boundaryline clearer than T2WI combined DWI. The detectability can be the highest when DCE-MRI combined with T2WI and DWI (93.2%, 41/44). The mean signal intensity of lung carcinomas was higher than that of postobstructive pneumonitis and atelectasis on DWI images (P <0.05). The mean ADC value of lung carcinomas was significantly lower than that of postobstructive pneumonitis and atelectasis (P<0.05).Conclusions: DCE-MRI may be more useful than T1WI, T2WI and CT in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma, and it has more advantages for differential diagnosis when combined with T2WI and DWI.
[Keywords] lung neoplasms；pulmonary atelectasis；pneumonia；magnetic resonance imaging；tomography, x-ray computed

DANG Baohua* Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

ZHAO Xin Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

ZHANG Xiaoan Department of Radiology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

*Correspondence to: Dang BH, E-mail: 382400313@qq.com

Conflicts of interest   None.

Received  2018-10-23
Accepted  2019-01-20
DOI: 10.12015/issn.1674-8034.2019.03.007
Cite this article as: Dang BH, Zhao X, Zhang XA. Dynamic contrast-enhanced MR imaging in differentiating postobstructive pneumonitis and atelectasis from central lung carcinoma. Chin J Magn Reson Imaging, 2019, 10(3): 195-200. DOI:10.12015/issn.1674-8034.2019.03.007.

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