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Clinical Article
Three dimensional fast spin echo accelerated with compressed sensing diagnoses cartilage lesions in knee
WANG Yakui  JIN Xiao  YUAN Huishu 

Cite this article as: Wang YK, Jin X, Yuan HS. Three dimensional fast spin echo accelerated with compressed sensing diagnoses cartilage lesions in knee. Chin J Magn Reson Imaging, 2019, 10(5): 352-355. DOI:10.12015/issn.1674-8034.2019.05.007.


[Abstract] Objective: To explore the diagnostic performance of modulated flip angle technique in refocused imaging with extended echo train (MATRIX) which is a three dimensional fast spin echo accelerated with compressed sensing for cartilage lesions of the knee joint.Materials and Methods: Sixty-two knee joints in 62 patients with knee joint injury were examined at 3.0 T magnetic resonance imaging (MRI) system before arthroscopic operation. Following conventional two dimensional fast spin echo (2D FSE) protocol, MATRIX including sagittal fat-suppressed proton density weighted image (PDWI) and non-fat-suppressed T1-weighted image (T1WI) was performed. And then axial and coronal images were reformatted after MATRIX scanning. 2D FSE and MATRIX images were independently reviewed by two radiologists. Signal to noise ratio (SNR) and contrast to noise ratio (CNR) of cartilage in 2D FSE and MATRIX images were calculated. Two radiologists independently graded cartilage lesions according to ICRS grade system, and then sensitivity, specificity and accuracy of 2D FSE and MATRIX were calculated with arthroscopy as the reference standard. Statistic analysis was performed with paired t test and McNemar test.Results: SNR of cartilage and CNR of cartilage/fluid and cartilage/marrow in MATRIX were significantly higher (P<0.01) than these in conventional 2D FSE. The sensitivity, specificity and accuracy of MATRIX and 2D FSE for diagnosing cartilage lesions were respectively 70.8%/59.2%, 75.5%/84.2% and 74.1%/76.6%. MATRIX had significantly higher sensitivity (P<0.01) but lower specificity (P<0.01) than 2D FSE. There was no significant differences (P=0.067) in accuracy between two sequences.Conclusions: MATRIX has significantly higher SNR and CNR for cartilage, and provides higher sensitivity but lower specificity for diagnosing cartilage lesions compared to conventional 2D FSE.
[Keywords] cartilage, articular;knee joint;magnetic resonance imaging

WANG Yakui Department of Radiology, Peking University Third Hospital, Beijing 100191, China

JIN Xiao Department of Radiology, Peking University Third Hospital, Beijing 100191, China

YUAN Huishu* Department of Radiology, Peking University Third Hospital, Beijing 100191, China

*Correspondence to: Yuan HS, E-mail: huishuy@bjmu.edu.cn

Conflicts of interest   None.

Received  2018-11-21
Accepted  2019-03-19
DOI: 10.12015/issn.1674-8034.2019.05.007
Cite this article as: Wang YK, Jin X, Yuan HS. Three dimensional fast spin echo accelerated with compressed sensing diagnoses cartilage lesions in knee. Chin J Magn Reson Imaging, 2019, 10(5): 352-355. DOI:10.12015/issn.1674-8034.2019.05.007.

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