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• Technical Article •
The clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train technology in diagnosis of deep venous thrombosis
ZHONG Jiali  PENG Ruchen  YANG Xinying  SONG Hailong  GAO Huihua 

Cite this article as: Zhong JL, Peng RC, Yang XY, et al. The clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train technology in diagnosis of deep venous thrombosis. Chin J Magn Reson Imaging, 2019, 10(5): 366-370. DOI:10.12015/issn.1674-8034.2019.05.010.


[Abstract] Objective: To investigate the clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train (MATRIX) sequences in diagnosis of deep venous thrombosis (DVT).Materials and Methods: In this prospective study, 20 patients clinically were diagnosed with deep venous thrombosis using ultrasound and D-dimer test from February 2018 to October 2018 in our hospital. 3D-T1WI-MATRIX and 3D-T1WI magnetization prepared rapid acquisition gradient echo (MPRAGE) were scanned by United Imaging uMR 770 3.0 T MRI system. The image quality of two sequences were evaluated with signal-to-noise ratio (SNR) and thrombosis vs blood contrast-to-noise ratio (CNR), and observed by two experienced radiologists through the demonstration and artifact of the venous thrombosis and the anatomical structure in five MPR axial pieces in inferior vena cava, common iliac vein, external iliac vein, upper femoral vein and middle-lower femoral vein among two sequences using five-point scale. Using SPSS 21.0 for statistical analysis.Results: In 20 cases of DVT patients, the SNR and CNR in 3D-T1WI-MATRIX were 117.20±65.40, 194.28±191.58, while the SNR and CNR in 3D-T1WI-MPARGE were 65.23±34.67, 57.24±54.38. The differences between them were statistically significant (P<0.05). The subjective image quality score among the two radiologists showed statistically significant differences in inferior vena cava, common iliac vein, external iliac vein, and middle-lower femoral vein in two sequences (P<0.05). there was no significant difference in upper femoral vein (P>0.05).Conclusions: As a black-blood sequence, 3D-T1WI-MATRIX is a new technique which has better SNR and CNR, less artifacts compared to 3D-T1WI-MPARGE which shows great value for DVT diagnosis.
[Keywords] venous thrombosis；lower extremity；magnetic resonance imaging

ZHONG Jiali Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, BeiJing 101149, China

PENG Ruchen* Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, BeiJing 101149, China

YANG Xinying Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, BeiJing 101149, China

SONG Hailong Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, BeiJing 101149, China

GAO Huihua Department of Radiology, Beijing Luhe Hospital Affiliated to Capital Medical University, BeiJing 101149, China

*Correspondence to: Peng RC, E-mail: 13501271260@163.com

Conflicts of interest   None.

Received  2018-10-22
Accepted  2019-03-19
DOI: 10.12015/issn.1674-8034.2019.05.010
Cite this article as: Zhong JL, Peng RC, Yang XY, et al. The clinical value of 3D-T1WI modulated flip angle technique in refocused imaging with extended echo train technology in diagnosis of deep venous thrombosis. Chin J Magn Reson Imaging, 2019, 10(5): 366-370. DOI:10.12015/issn.1674-8034.2019.05.010.

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