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• Clinical Article •
The correlation analysis between basilar artery bending angles and its plaque formation
LIN Huihua  YANG Benqiang  DUAN Yang 

Cite this article as: Lin HH, Yang BQ, Duan Y. The correlation analysis between basilar artery bending angles and its plaque formation. Chin J Magn Reson Imaging, 2019, 10(6): 410-414. DOI:10.12015/issn.1674-8034.2019.06.003.


[Abstract] Objective: To investigate the correlation between basilar artery (BA) bending angles and plaque formation with three dimensions time of flight magnetic resonance angiography (3D TOF MRA) and high resolution magnetic resonance imaging (HR-MRI).Materials and Methods: Clinical and imaging data of patients with new isolated pontine infarctions confirmed by diffusion weighted imaging (DWI) from October 2015 to June 2018 were retrospectively collected. The BA angles were divided into the lateral angles (from the anteroposterior view) and anterior angles (from the lateral view) on the 3D TOF MRA image. BA culprit plaque was defined as if it was on the same slice or adjacent upper or lower slice of pontine infarcts. BA plaque location was divided into ventral, dorsal, and lateral (left or right) sides of the vessel. All patients were divided into no plaque group (22 cases) and plaque group (75 cases) according to whether there was BA plaque or not. Univariate analysis and multivariate Logistic regression analysis were performed to explore the independent factors associated wirh the presence of BA plaque. One-way analysis of variance was used to compare the variables of BA plaque location (no plaque, ventral, dorsal, lateral).Results: There were 22 patients (23%) without BA plaques and 75 patients (77%) with BA plaques. BA plaques were located at ventral wall (3%, n=3), dorsal wall (42%, n=41), lateral wall (32%, n=31). Univariate analysis showed there were significant difference in BA lateral angles, BA anterior angles and discharge modified Rankin Scale (mRS) score between patients with and without a BA plaque (P<0.05). Multivariate Logistic regression analysis showed BA lateral angles and anterior angles were independent risk factors for plaque formation (BA anterior angle: OR value=0.095, 95%CI=1.032-1.171; BA lateral angle: OR value=0.132, 95%CI=1.053-1.236). There were significant differences in anterior angles and lateral angles between different BA plaque location (no plaque, ventral, dorsal and lateral).Conclusions: Greater the anterior angle (from the lateral view) may enhance dorsal plaque formation. Greater the lateral angle (anteroposterior view) may enhance lateral plaque formation.
[Keywords] magnetic resonance imaging；atherosclerosis；plaque；basilar artery；bengding angle；hemodynamics

LIN Huihua Department of Radiology, Northern Theater Command General Hospital of PLA, Shenyang 110016, China

YANG Benqiang Department of Radiology, Northern Theater Command General Hospital of PLA, Shenyang 110016, China

DUAN Yang* Department of Radiology, Northern Theater Command General Hospital of PLA, Shenyang 110016, China

*Correspondence to: Duan Y, E-mail: duanyang100@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Liaoning Natural Science Foundation Project No. 201602768
Received  2018-09-10
Accepted  2018-12-12
DOI: 10.12015/issn.1674-8034.2019.06.003
Cite this article as: Lin HH, Yang BQ, Duan Y. The correlation analysis between basilar artery bending angles and its plaque formation. Chin J Magn Reson Imaging, 2019, 10(6): 410-414. DOI:10.12015/issn.1674-8034.2019.06.003.

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