Share：
Share this content in WeChat
X
[Chinese][PDF]937155
• Clinical Article •
Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging
WANG Hui  XU Lei  HE Yi  DONG Jianzeng 

Cite this article as: Wang H, Xu L, He Y, et al. Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(6): 415-419. DOI:10.12015/issn.1674-8034.2019.06.004.


[Abstract] Objective: To evaluate the changes of cardiac morphology and left ventricular diastolic function in patients with apical hypertrophic cardiomyopathy (AHCM) by cardiac magnetic resonance imaging (CMRI).Materials and Methods: We retrospectively analyzed the patients in our hospital who underwent CMRI, electrocardiogram (ECG) and echocardiography during the time between September 2015 to July 2018. Sixty nine cases AHCM and 25 health controls were picked out. The left ventricular ejection fraction (LVEF), left ventricular myocardial mass, thickness of left apical ventricular wall, left atrial end systolic volume index (LAESV), left atrial peak global longitudinal strain (LAPGLS), left atrial peak global circumferential strain (LAPGCS), and left atrium fraction area change (FAC) were compared between the two groups. And the correlation between LAPGLS, LAPGCS and other left atrium and ventricular structural and functional parameters were analyzed.Results: In AHCM group, the thickness of apical ventricular wall, myocardial mass, LVEF and LAESV were significantly higher than those of normal control group, while LAPGLS and FAC were lower than those of the normal control group. The differences between the two groups were statistically significant, while LAPGCS between the two groups had no difference.Conclusions: In patients with apical hypertrophic cardiomyopathy, left ventricular diastolic function (LAPGLS) decreased, while left atrial systolic function (LAPGCS) did not change significantly. FAC of the left atrium can be used as an alternative indicator of LAPGLS to determine whether the diastolic function of the left ventricle is declined.
[Keywords] magnetic resonance imaging；apical hypertrophic cardiomyopathy；left atrial strain；left ventricular diastolic function

WANG Hui Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

XU Lei* Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

HE Yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

DONG Jianzeng Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

*Correspondence to: Xu L, E-mail: leixu2001@hotmail.com

Conflicts of interest   None.

Received  2018-12-29
Accepted  2019-03-05
DOI: 10.12015/issn.1674-8034.2019.06.004
Cite this article as: Wang H, Xu L, He Y, et al. Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(6): 415-419. DOI:10.12015/issn.1674-8034.2019.06.004.

[1]
Sakamoto T, Tei C, Murayama M, et al. Giant T wave inversion as a manifestation of asymmetrical apical hypertrophy (AAH) of the left ventricle. Echocardiographic and ultrasono-cardiotomographic study. Jpn Heart J, 1976, 17(5): 611-629.
[2]
Yamaguchi H, Ishimura T, Nishiyama S, et al. Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): ventriculographic and echocardiographic features in 30 patients. Am J Cardiol, 1979, 44(3): 401-412.
[3]
Ho HH, Lee KL, Lau CP, et al. Clinical characteristics of and long-term outcome in Chinese patients with hypertrophic cardiomyopathy. Am J Med, 2004, 116(1): 19-23.
[4]
Fattori R, Biagini E, Lorenzini M, et al. Significance of magnetic resonance imaging in apical hypertrophic cardiomyopathy. Am J Cardiol, 2010, 105(11): 1592-1596.
[5]
Pons-Llado G, Carreras F, Borras X, et al. Comparison of morphologic assessment of hypertrophic cardiomyopathy by magnetic resonance versus echocardiographic imaging. Am J Cardiol, 1997, 79(12): 1651-1656.
[6]
Flett AS, Maestrini V, Milliken D, et al. Diagnosis of apical hypertrophic cardiomyopathy: T-wave inversion and relative but not absolute apical left ventricular hypertrophy. Int J Cardiol, 2015, 183: 143-148.
[7]
Wu B, Lu M, Zhang Y, et al. CMR assessment of the left ventricle apical morphology in subjects with unexplainable giant T-wave inversion and without apical wall thickness >/=15 mm. Eur Heart J Cardiovasc Imaging, 2017, 18(2): 186-194.
[8]
袁思殊，李志伟，夏黎明.心尖肥厚型心肌病的MRI与超声心动图对比研究.磁共振成像, 2015, 6(3): 187-193.
[9]
中华医学会心血管病学分会中国成人肥厚型心肌病诊断与治疗指南编写组，中华心血管病杂志编辑委员会.中国成人肥厚型心肌病诊断与治疗指南.中华心血管病杂志, 2017, 45(12): 1015-1032.
[10]
Nagueh SF, Smiseth OA, Appleton CP, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: An update from the American society of echocardiography and the European association of cardiovascular imaging. Eur Heart J Cardiovasc Imaging, 2016, 17(12): 1321-1360.
[11]
Singh A, Addetia K, Maffessanti F, et al. LA strain for categorization of LV diastolic dysfunction. JACC Cardiovasc Imaging, 2017, 10(7): 735-743.
[12]
Sanchis L, Andrea R, Falces C, et al. Differential clinical implications of current recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr, 2018, 31(11): 1203-1208.
[13]
Cameli M, Mandoli GE, Loiacono F, et al. Left atrial strain: a new parameter for assessment of left ventricular filling pressure. Heart Fail Rev, 2016, 21(1): 65-76.
[14]
Noureldin RA, Liu S, Nacif MS, et al. The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance. J Cardiovasc Magn Reson, 2012, 14: 17.
[15]
Chacko BR, Karur GR, Connelly KA, et al. Left ventricular structure and diastolic function by cardiac magnetic resonance imaging in hypertrophic cardiomyopathy. Indian Heart J, 2018, 70(1): 75-81.
[16]
Spirito P, Maron BJ, Chiarella F, et al. Diastolic abnormalities in patients with hypertrophic cardiomyopathy: relation to magnitude of left ventricular hypertrophy. Circulation, 1985, 72(2): 310-316.
[17]
Blume GG, McLeod CJ, Barnes ME, et al. Left atrial function: physiology, assessment, and clinical implications. Eur J Echocardiogr, 2011, 12(6): 421-430.
[18]
Hoit BD. Left atrial size and function: role in prognosis. J Am Coll Cardiol, 2014, 63(6): 493-505.
[19]
Gan GCH, Ferkh A, Boyd A, et al. Left atrial function: evaluation by strain analysis. Cardiovasc Diagn Ther, 2018, 8(1): 29-46.
[20]
Bagge L, Blomstrom P, Jideus L, et al. Left atrial function after epicardial pulmonary vein isolation in patients with atrial fibrillation. J Interv Card Electrophysiol, 2017, 50(2): 195-201.

PREV The correlation analysis between basilar artery bending angles and its plaque formation
NEXT Correlation of mammography, MRI features and molecular typing of breast cancer
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn