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• Clinical Article •
Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging
WANG Hui  XU Lei  HE Yi  DONG Jianzeng 

Cite this article as: Wang H, Xu L, He Y, et al. Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(6): 415-419. DOI:10.12015/issn.1674-8034.2019.06.004.


[Abstract] Objective: To evaluate the changes of cardiac morphology and left ventricular diastolic function in patients with apical hypertrophic cardiomyopathy (AHCM) by cardiac magnetic resonance imaging (CMRI).Materials and Methods: We retrospectively analyzed the patients in our hospital who underwent CMRI, electrocardiogram (ECG) and echocardiography during the time between September 2015 to July 2018. Sixty nine cases AHCM and 25 health controls were picked out. The left ventricular ejection fraction (LVEF), left ventricular myocardial mass, thickness of left apical ventricular wall, left atrial end systolic volume index (LAESV), left atrial peak global longitudinal strain (LAPGLS), left atrial peak global circumferential strain (LAPGCS), and left atrium fraction area change (FAC) were compared between the two groups. And the correlation between LAPGLS, LAPGCS and other left atrium and ventricular structural and functional parameters were analyzed.Results: In AHCM group, the thickness of apical ventricular wall, myocardial mass, LVEF and LAESV were significantly higher than those of normal control group, while LAPGLS and FAC were lower than those of the normal control group. The differences between the two groups were statistically significant, while LAPGCS between the two groups had no difference.Conclusions: In patients with apical hypertrophic cardiomyopathy, left ventricular diastolic function (LAPGLS) decreased, while left atrial systolic function (LAPGCS) did not change significantly. FAC of the left atrium can be used as an alternative indicator of LAPGLS to determine whether the diastolic function of the left ventricle is declined.
[Keywords] magnetic resonance imaging；apical hypertrophic cardiomyopathy；left atrial strain；left ventricular diastolic function

WANG Hui Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

XU Lei* Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

HE Yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

DONG Jianzeng Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

*Correspondence to: Xu L, E-mail: leixu2001@hotmail.com

Conflicts of interest   None.

Received  2018-12-29
Accepted  2019-03-05
DOI: 10.12015/issn.1674-8034.2019.06.004
Cite this article as: Wang H, Xu L, He Y, et al. Evaluation of the left atrioventricular structure, function and correlation in patients with apical hypertrophic cardiomyopathy by cardiac magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(6): 415-419. DOI:10.12015/issn.1674-8034.2019.06.004.

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