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Clinical Article
The difference of surrounding edema between benign tmor-tumor-like lesions and malignant tumors: Evaluated by MRI
GAO Sai  YANG Zhitao  LI Xiang  CHEN Haisong  XU Wenjian 

Cite this article as: Gao S, Yang ZT, Li X, et al. The difference of surrounding edema between benign tmor-tumor-like lesions and malignant tumors: evaluated by MRI. Chin J Magn Reson Imaging, 2019, 10(6): 430-434. DOI:10.12015/issn.1674-8034.2019.06.007.


[Abstract] Objective: To analyze the differences of surrounding marrow and soft tissue edema between benign bone tumor-tumor-like lesions and malignant bone tumors, in order to help differentiate the benign and malignant.Materials and Methods: 121 cases of bone tumors and tumor like lesions confirmed by surgery were retrospective reviewed, according to pathology. The lesions were divided into the benign group and malignant group. The incidences of bone marrow and soft tissue edema around the lesion were analyzed. The ratio of the largest diameter of bone marrow and soft tissue edema to the largest diameter of tumor was calculated. The data of two groups were analyzed by non-parametrie test.Results: There were 63 patients in the benign group and 58 in the malignant group. There was no statistically significant difference of the incidence of bone marrow edema in the benign and malignant group (65.08%, 58.62%, χ2=0.535, P>0.05); the incidence of soft tissue edema in the malignant group is greater than that in the benign group (81.03%, 63.49%, χ2=4.6, P<0.05). For the ratio of the largest diameter of bone marrow edema to that of the tumor, the benign group is larger than the malignant group (the median of the ratio is 0.69, 0.425, P<0.05). For the ratio of thelargest diameter of soft tissue edema to the that of the tumor, there was no significant difference between benign and malignant group (the median of the ratio is 0.415, 0.3, P>0.05).Conclusions: Bone marrow and soft tissue edema can be found surrounding around both the benign and malignant bone tumors, the differences are: soft tissue edema is more common in the malignant tumors, bone marrow edema is more pronounced in the benign group (The ratio of the largest diameter of bone marrow edema to the that of the tumor in the benign group is greater than that in the malignant group).
[Keywords] bone neoplasms;magnetic resonance imaging;bone marrow edema;soft tissue edema

GAO Sai Qingdao University, Qingdao 266003, China

YANG Zhitao Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China

LI Xiang Department of Ultrasound, the Affiliated Hospital of Qingdao University, Qingdao 266003, China

CHEN Haisong* Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China

XU Wenjian Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China

*Correspondence to: Chen HS, E-mail: chs368@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81571673, 81671658
Received  2019-01-30
Accepted  2019-04-30
DOI: 10.12015/issn.1674-8034.2019.06.007
Cite this article as: Gao S, Yang ZT, Li X, et al. The difference of surrounding edema between benign tmor-tumor-like lesions and malignant tumors: evaluated by MRI. Chin J Magn Reson Imaging, 2019, 10(6): 430-434. DOI:10.12015/issn.1674-8034.2019.06.007.

[1]
上官景俊,徐文坚,李文, 等. 骨肿瘤与瘤样病变周围组织影像表现分析. 中华放射学杂志, 2011, 45(5): 463-467.
[2]
马玲,孟悛非. 恶性骨肿瘤周围水肿的MRI表现、机制与意义. 中国骨肿瘤骨病, 2002, 1(3): 153-156.
[3]
Kroon HM, Bloem JL, Holscher HC, et al. MR imaging of edema accompanying benign and malignant bone tumors. Skeletal Radiol, 1994, 23(4): 261-269.
[4]
James SLJ, Panicek DM, Davies AM. Bone marrow oedema associated with benign and malignant bone tumours. Eur J Radiol, 2008, 67(1):11-21.
[5]
Janzen L, Logan PM, O'Connell JX, et al. Intramedullary chondroid tumors of bone: correlation of abnormal peritumoral marrow and soft-tissue MRI signal with tumor type. Skeletal Radiol, 1997, 26(2): 100-106.
[6]
Shinmura K, Ishida T, Goto T, et al. Expression of cyclooxygenase-2 in chondroblastoma: immunohistochemical analysis with special emphasis on local inflammatory reaction. Virchows Arch, 2004, 444(1): 28-35.
[7]
王毅. 软骨母细胞瘤的DR、CT及MRI表现及诊断分析. 中国CT和MRI杂志, 2017, 15(2): 109-112.
[8]
Yamamura S, Sato K, Sugiura H, Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging. Can, 2015, 79(2): 255-261.
[9]
杨自力,王伟唯,陈海松. MRI对软组织未分化多形性肉瘤的诊断价值. 医学影像学杂志, 2018, 28(10): 1740-1744.
[10]
James SLJ, Hughes RJ, Ali KE, et al. MRI of bone marrow oedema associated with focal bone lesions. Clin Radiol, 2006, 61(12): 1003-1009.
[11]
张晓莉,吴刚,谢如意, 等. 体素内不相干运动成像和扩散峰度成像在下肢良恶性骨与软组织肿瘤鉴别诊断中的价值. 磁共振成像, 2018, 9(7): 525-532.
[12]
陈海松,韩燕,耿青, 等. 良恶性骨肿瘤的MRI鉴别诊断. 磁共振成像, 2014, 5(4): 291-295.
[13]
姜前,江浩,丁晓毅, 等. MRI动态增强在鉴别原发性骨肉瘤与瘤周水肿的价值(与病理标本对照). 中国医学计算机成像杂志, 2001, 7(6): 401-405.
[14]
Steen RG. Edema and tumor perfusion: characterization by quantitative 1H MR imaging. Am J Roentgenol, 1992, 158(2): 259-264.
[15]
Panicek DM, Gatsonis C, Rosenthal DI, et al. CT and MR imaging in the local staging of primary malignant musculoskeletal neoplasms: Report of the Radiology Diagnostic Oncology Group. Radiology, 1997, 202(1): 237-246.
[16]
段舒怀,任翠萍. MRI对骨肿瘤及软组织肿瘤的诊断价值. 中国CT和MRI杂志, 2018, 16(5): 131-133, 150.
[17]
徐海. 骨肿瘤影像学与病理学相关性研究. 实用癌症杂志, 2016, 31(6): 967-971.
[18]
王小清,刘贺国. 骨肿瘤影像学与病理学的相关性研究. 实用癌症杂志, 2017, 32(1): 156-158.
[19]
余泽祥. 不同病理类型脊柱骨肿瘤影像学特征及诊断价值分析. 湖南师范大学学报(医学版), 2018, 15(6): 171-174.

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