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• Clinical Article •
The value of DWI and minimum ADC value in grading diagnosis of adult intracranial ependymoma
HAN Lei  KE Xiaoai  ZHOU Qing  ZHOU Junlin 

Cite this article as: Han L, Ke XA, Zhou Q, et, al. The value of DWI and minimum ADC value in grading diagnosis of adult intracranial ependymoma. Chin J Magn Reson Imaging, 2019, 10(7): 481-485. DOI:10.12015/issn.1674-8034.2019.07.001.


[Abstract] Objective: To investigate the value of diffusion weighted imaging (DWI) and minimum apparent diffusion coefficient (ADC) value in the differential diagnosis of adult intracranial ependymoma and anaplastic ependymoma.Materials and Methods: Retrospective analysis of preoperative clinical data, DWI characteristics, and measurement of tumors in 15 cases of adult intracranial ependymoma and 10 cases of interstitial ependymoma confirmed by surgery and pathology from January 2015 to March 2019 in our hospital. The minimum ADC value of the substantial part and the difference between the two were compared using the receiver operating characteristic curve (ROC curve) to analyze the diagnostic performance of the minimum ADC value.Results: In 15 cases of ependymoma, 9 cases of DWI showed a slightly higher signal in the parenchyma, and 6 cases showed an equal low signal, and the minimum ADC value was (0.992±0.191)×10-3 mm2/s. In 10 cases of anaplastic ependymoma, 7 cases of parenchyma showed slightly higher or higher signal on DWI, 3 cases showed slightly lower signal, and the minimum ADC value was (0.725±0.101) ×10-3 mm2/s. The difference in the minimum ADC value of the parenchymal part of the tumor was statistically significant (t=4.563, P<0.001). The results of ROC curve showed that the AUC value was 0.883, and the minimum ADC value was 0.872×10-3 mm2/s. The sensitivity of differential diagnosis of the two tumors was 80% and the specificity was 90%.Conclusions: DWI and minimum ADC value can be used as a new method for differential diagnosis of adult intracranial ependymoma and anaplastic ependymoma.
[Keywords] ependymoma；magnetic resonance imaging；diagnosis, differential

HAN Lei Department of Radiology, Lanzhou University Second Hospital, Lanzhou Second Clinical School, Lanzhou University Key Laboratory of Medical Imaging of Gansu Province, Lanzhou 730030, China

KE Xiaoai Department of Radiology, Lanzhou University Second Hospital, Lanzhou Second Clinical School, Lanzhou University Key Laboratory of Medical Imaging of Gansu Province, Lanzhou 730030, China

ZHOU Qing Department of Radiology, Lanzhou University Second Hospital, Lanzhou Second Clinical School, Lanzhou University Key Laboratory of Medical Imaging of Gansu Province, Lanzhou 730030, China

ZHOU Junlin* Department of Radiology, Lanzhou University Second Hospital, Lanzhou Second Clinical School, Lanzhou University Key Laboratory of Medical Imaging of Gansu Province, Lanzhou 730030, China

*Correspondence to: Zhou JL, E-mail: zjl601@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the National Natural Science Foundation of China No. 81772006
Received  2019-04-16
Accepted  2019-05-28
DOI: 10.12015/issn.1674-8034.2019.07.001
Cite this article as: Han L, Ke XA, Zhou Q, et, al. The value of DWI and minimum ADC value in grading diagnosis of adult intracranial ependymoma. Chin J Magn Reson Imaging, 2019, 10(7): 481-485. DOI:10.12015/issn.1674-8034.2019.07.001.

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