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• Clinical Article •
The applied value of multiparametric MRI in differentiating uterine carcinosarcoma from low risk endometrial carcinoma
SHEN Yiqing  LÜ Fajin  LIU Xiaoxi  XIONG Yulin 

Cite this article as: Shen YQ, Lü FJ, Liu XX, et, al. The applied value of multiparametric MRI in differentiating uterine carcinosarcoma from low risk endometrial carcinoma. Chin J Magn Reson Imaging, 2019, 10(7): 535-539. DOI:10.12015/issn.1674-8034.2019.07.011.


[Abstract] Objective: To explore the applied value of quantitative and qualitative magnetic resonance imaging (MRI) parameters in differentiating uterine carcinosarcoma (CS) from low risk endometrial carcinoma (EC).Materials and Methods: Eighteen CS and 30 low risk EC confirmed by surgery were retrospectively analysed. The following MRI features of the tumors were evaluated: tumor morphology, maximum tumor diameter, ET/AP, the integrity of junction zone, hemorrhagic, necrotic/cystic components, flow voids, mean ADC values (mADC), relative ADC values (rADC), maximum relative enhancement ratio (MRER) and Washout.Results: There were significant differences between CS and EC in the following qualitative parameters: hemorrhagic, necrotic/cystic components and flow voids (P<0.05). For quantitative MRI parameters, maximum dimension, ET/AP, MRER and Washout could significantly distinguish CS from low risk EC (P<0.05). According to the receiver operating characteristic (ROC) curves, when the cut-off values of maximum dimension, ET/AP, MRER and Washout were 37.5 mm, 0.474, 1.299 and 0.021, the sensitivity and specificity of the diagnosis were 83.3%, 83.3%; 88.9%, 83.3%; 94.4%, 96.7%; 100.0%, 72.2%; respectively.Conclusions: Qualitative and quantitative MRI parameters were of great value in differentiating CS from low risk EC. The maximum diameter, ET/AP, MRER and Washout could be used as optimization parameters to provide imaging information for adequate clinical treatment.
[Keywords] uterine neoplasms；carcinosarcoma；endometrial neoplasms；magnetic resonance imaging；diagnosis, differential

SHEN Yiqing Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

LÜ Fajin* Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

LIU Xiaoxi Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

XIONG Yulin Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

*Correspondence to: Lü FJ, E-mail: fajinlv@163.com

Conflicts of interest   None.

Received  2019-01-21
Accepted  2019-05-21
DOI: 10.12015/issn.1674-8034.2019.07.011
Cite this article as: Shen YQ, Lü FJ, Liu XX, et, al. The applied value of multiparametric MRI in differentiating uterine carcinosarcoma from low risk endometrial carcinoma. Chin J Magn Reson Imaging, 2019, 10(7): 535-539. DOI:10.12015/issn.1674-8034.2019.07.011.

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