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• Clinical Article •
Diagnostic value of the combination of IVIM-DWI and DCE-MRI in pelvic lymphatic metastasis of rectal cancer
KANG Liqing  GUO Suyin  ZHAO Meng  LIU Fenghai  XING Rongge  JIANG Guosheng  LI Guoce 

Cite this article as: Kang LQ, Guo SY, Zhao M, et al. Diagnostic value of the combination of IVIM-DWI and DCE-MRI in pelvic lymphatic metastasis of rectal cancer. Chin J Magn Reson Imaging, 2019, 10(8): 583-588. DOI:10.12015/issn.1674-8034.2019.08.005.


[Abstract] Objective: To investigate the value of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the identification of pelvic lymphatic metastasis in rectal cancer.Materials and Methods: 63 pelvic lymph nodes of 45 patients with rectal cancer were divided into metastasis group (35 pieces) and non-metastasis group (28 pieces) by pathology, and the parameters of IVIM (ADC, D, D* and f values) and DCE-MRI (Ktrans, Ve and Kep values) of the two groups were compared.Results: The mean D and D* value of metastatic lymph nodes were significantly lower than those of non-metastatic lymph nodes, and the mean f value of metastatic lymph nodes was significantly higher than that of non-metastatic lymph nodes (P<0.05). The mean Ktrans and Ve value of metastatic lymph nodes were higer than those of non-metastatic lymph nodes (P< 0.05). The factors adopted in the Logistic regression equation of IVIM-DWI and DCE-MRI were D value and Ktrans value respectively. The AUC of D, Ktrans value and their combination to diagnose pelvic lymph node metastasis were 0.822, 0.789 and 0.923, respectively. The sensitivity in diagnosing pelvic lymph node metastasis of the three methods were 68.6%, 85.7% and 91.4%, and the specificity were 85.7%, 67.9% and 82.1%, respectively.Conclusions: D value of IVIM-DWI and Ktrans value of DCE-MRI have great value in diagnosing pelvic lymphatic metastasis in rectal cancer, and the combination of the two methods might improve the diagnostic efficiency.
[Keywords] intravoxel incoherent motion；diffusion-weighted imaging；dynamic contrast-enhanced；magnetic resonance imaging；lymph node；rectal neoplasms

KANG Liqing* Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, Cangzhou 061000, China

GUO Suyin Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, Cangzhou 061000, China

ZHAO Meng Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, Cangzhou 061000, China

LIU Fenghai Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, Cangzhou 061000, China

XING Rongge Department of Pathology, Cangzhou Central Hospital, Cangzhou 061000, China

JIANG Guosheng Department of Anorectal Surgery, Cangzhou Central Hospital, Cangzhou 061000, China

LI Guoce Department of Magnetic Resonance Imaging, Cangzhou Central Hospital, Cangzhou 061000, China

*Correspondence to: Kang LQ, E-mail: 1513203473@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Hebei Province Science and Technology Huimin Project No. 152777100D
Received  2019-02-18
Accepted  2019-05-08
DOI: 10.12015/issn.1674-8034.2019.08.005
Cite this article as: Kang LQ, Guo SY, Zhao M, et al. Diagnostic value of the combination of IVIM-DWI and DCE-MRI in pelvic lymphatic metastasis of rectal cancer. Chin J Magn Reson Imaging, 2019, 10(8): 583-588. DOI:10.12015/issn.1674-8034.2019.08.005.

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