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• Clinical Article •
Application value of magnetic resonance T2 mapping imaging in evaluation of knee osteoarthritis cartilage injury
SUN Zhaonan  WANG Xuchao  XU Min  XU Chang  WANG Wei 

Cite this article as: Sun ZN, Wang XC, Xu M, et al. Application value of magnetic resonance T2 mapping imaging in evaluation of knee osteoarthritis cartilage injury. Chin J Magn Reson Imaging, 2019, 10(9): 680-684. DOI:10.12015/issn.1674-8034.2019.09.008.


[Abstract] Objective: To observe the change of T2 value in cartilage injury and the diagnostic value and clinical significance of T2 mapping imaging in osteoarthritis (OA) cartilage injury.Materials and Methods: Sixty patients with knee osteoarthritis were selected as the observation group and thirty healthy volunteers were selected as the control group. The two group patients underwent GE Signa 3.0 T MRI scanning including conventional and T2 mapping imaging sequence. The average T2 value of cartilage in 7 regions including weight-bearing area and non-weight-bearing area of medial and lateral femoral condyle, medial tibial plateau, lateral tibial plateau and patella cartilage were measured respectively.Results: The average T2 values of cartilage in regions in the observation group were higher compared with the control group (P<0.05). Except for the medial femoral condyle of the control group, the average T2 values of the weight-bearing areas of medial and lateral femoral condyle of the observation group and lateral femoral condyle of the control group were higher than those of the corresponding non-weight-bearing areas (P<0.05). The average T2 value of superficial cartilage was higher than that of deep cartilage in the same region except for the weight-bearing area of medial femoral condyle in the observation group (P<0.05). The average T2 values of the weight-bearing areas of medial and lateral femoral condyle in the severe and mild OA group were both higher compared with the normal group (P<0.05), however, there was no significant difference in the T2 value of weight-bearing areas of medial and lateral femoral condyle between the severe OA group and the mild OA group (P>0.05).Conclusions: T2 mapping can detect the changes of cartilage T2 value and it is helpful for OA patients to start treatment without delay, monitor disease progress and conduct the follow-up of cartilage repair.
[Keywords] cartilage, articular；osteoarthritis；knee；magnetic resonance imaging

SUN Zhaonan Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

WANG Xuchao Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

XU Min Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

XU Chang Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

WANG Wei* Department of Magnetic Resonance, the First Affiliated Hospital of Harbin Medical University, Harbin 150001, China

*Correspondence to: Wang W, E-mail: 1391082196@qq.com

Conflicts of interest   None.

Received  2019-04-09
Accepted  2019-06-23
DOI: 10.12015/issn.1674-8034.2019.09.008
Cite this article as: Sun ZN, Wang XC, Xu M, et al. Application value of magnetic resonance T2 mapping imaging in evaluation of knee osteoarthritis cartilage injury. Chin J Magn Reson Imaging, 2019, 10(9): 680-684. DOI:10.12015/issn.1674-8034.2019.09.008.

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