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• Paying a Tribute to 70 Years of Healthcare Development •
The review and the future of functional magnetic resonance imaging
DU Xiaoxia  QIN Zhaoxia 

Cite this article as: Du XX, Qin ZX. The review and the future of functional magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(10): 721-726. DOI:10.12015/issn.1674-8034.2019.10.001.


[Abstract] Magnetic resonance functional imaging generally refers to functional magnetic resonance imaging (fMRI) based on blood oxygen level dependence (BOLD), which responds to changes in deoxyhemoglobin concentration consequent to task-induced or spontaneous modulation of neural metabolism. Since its inception in 1990, fMRI as a non-invasive tool with good spatial resolution, has been used in a large number of studies in the cognitive neurosciences, clinical psychiatry/psychology, and presurgical planning; and fMRI is increasingly being used as a biomarker for disease, and to monitor therapy or for studying pharmacological efficacy. Recently, pattern classification and other statistical methods have been applied to data analysis of functional imaging, real-time feedback has developed rapidly, and fMRI will be more involved in clinical medicine. This paper reviews the methods, the application and the future of fMRI.
[Keywords] functional magnetic resonance imaging；brain function；cognitive neuroscience；mental illness；blood oxygen level dependent

DU Xiaoxia * Shanghai Key Laboratory of Magnetic Resonance & Department of Physics, School of Physics and Electronic Science East China Normal University, Shanghai 200062, China

QIN Zhaoxia Shanghai Key Laboratory of Magnetic Resonance & Department of Physics, School of Physics and Electronic Science East China Normal University, Shanghai 200062, China

*Corresponding to: Du XX, E-mail: xxdu@phy.ecnu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81571658
Received  2019-09-02
DOI: 10.12015/issn.1674-8034.2019.10.001
Cite this article as: Du XX, Qin ZX. The review and the future of functional magnetic resonance imaging. Chin J Magn Reson Imaging, 2019, 10(10): 721-726. DOI:10.12015/issn.1674-8034.2019.10.001.

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