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• Clinical Article •
Study of the relationship between vascular wall changes of vertebrobasilar atherosclerosis and ischemic stroke by HRMR-VWI
SHI Zengqiang  JIA Lin  JIA Wenxiao  HAN Bingyan  WANG Yunling 

Cite this article as: Shi ZQ, Jia L, Jia WX, et al. Study of the relationship between vascular wall changes of vertebrobasilar atherosclerosis and ischemic stroke by HRMR-VWI. Chin J Magn Reson Imaging, 2019, 10(10): 743-747. DOI:10.12015/issn.1674-8034.2019.10.005.


[Abstract] Objective: To investigate the relationship between vertebral-basal artery atherosclerotic vascular remodeling pattern, plaque burden, distribution characteristics and cerebral infarction by high resolution magnetic resonance vessel wall imaging (HRMR-VWI).Materials and Methods: Thirty-two patients with post-circulation acute cerebral infarction were enrolled, and routine magnetic resonance imaging (including DWI sequence) and HRMR-VWI were performed to confirm the presence of cerebral infarction in the posterior circulation blood supply area and to measure the vessel wall of the responsible vessel and calculate the remodeling index (RI) of the vessel area at the narrowest point/vascular area at the reference. Compare the area of negative and positive remolding vascular plaque area, plaque burden, and observe the location distribution and enhancement characteristics of responsible plaque.Results: HRMR-VWI found 30 patients with vertebral-basal atherosclerotic plaque, including 18 cases of basilar atherosclerotic plaque, 12 cases of vertebral artery (intracranial part) atherosclerotic plaque, and 2 cases of parabrachial infarction without obvious plaques. Responsible vascular remodeling was performed in 21 patients, negative remodeling in 7 patients, and no remodeling in 2 patients. The plaque area (6.32±3.19) mm2 and plaque load (0.51±0.13)% of the positive remodeling group were larger than the plaque area of the negative remodeling group (2.14± 1.43) mm2 and the load (0.28±0.19)%. Vertebral-basal atherosclerotic plaques often occur around the opening of the branch of the perforating artery and are more common in the dorsolateral side.Conclusions: HRMR-VWI can be used as an important examination method for the diagnosis of post-circulation acute cerebral infarction.
[Keywords] vertebral-basal artery system；atherosclerotic plaque；high resolution magnetic resonance vascular wall imaging；stroke；magnetic resonance imaging

SHI Zengqiang Imaging Center, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

JIA Lin Imaging Center, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

JIA Wenxiao Imaging Center, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

HAN Bingyan Imaging Center, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

WANG Yunling * Imaging Center, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China

*Correspondence to: Wang YL, E-mail: 1079806994@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Autonomous Region Regional Collaborative Innovation Project (Technology Aids Program) No.2018E02063
Received  2019-03-26
DOI: 10.12015/issn.1674-8034.2019.10.005
Cite this article as: Shi ZQ, Jia L, Jia WX, et al. Study of the relationship between vascular wall changes of vertebrobasilar atherosclerosis and ischemic stroke by HRMR-VWI. Chin J Magn Reson Imaging, 2019, 10(10): 743-747. DOI:10.12015/issn.1674-8034.2019.10.005.

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