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Progress of diffusion imaging in neonatal hypoxic-ischemic encephalopathy
HAN Yuxuan  WU Peng  HE Xiaoning  XIAO Juan  YANG Chao 

Cite this article as: Han YX, Wu P, He XN, et al. Progress of diffusion imaging in neonatal hypoxic-ischemic encephalopathy. Chin J Magn Reson Imaging, 2019, 10(10): 783-786. DOI:10.12015/issn.1674-8034.2019.10.014.


[Abstract] Magnetic resonance imaging (MRI) is sensitive to detect hypoxic-ischemic encephalopathy (HIE). Conventional magnetic resonance imaging technology can accurately describe the vasogenic edema in the injured area of HIE, presenting as low signal on T1WI and high signal on T2WI. However, in the early stage of brain injury, there was no significant change in TIWI and T2WI for the cytopathic edema with only slight increase in brain tissue moisture. Compared with conventional MRI, magnetic resonance diffusion imaging based on the diffusion of water molecules can better reflect the microstructure of human tissue and the movement of water molecules inside and outside the cell, and it is easier to detect early HIE. The prospect of diffusion weighted imaging (DWI), diffusion tensor imaging (DTI) and diffusion kurtosis imaging (DKI) in the diagnosis of HIE is worth exploring.
[Keywords] diffusion weighted imaging；diffusion tensor imaging；diffusion kurtosis imaging；asphyxia neonatorum

HAN Yuxuan Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116000, China

WU Peng Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116000, China

HE Xiaoning Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116000, China

XIAO Juan Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116000, China

YANG Chao * Department of Radiology, the Second Hospital of Dalian Medical University, Dalian 116000, China

*Corresponding to: Yang C, E-mail: dryangchao@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No.81771663 Liaoning Province Natural Science Found No.20170540237
Received  2019-03-10
DOI: 10.12015/issn.1674-8034.2019.10.014
Cite this article as: Han YX, Wu P, He XN, et al. Progress of diffusion imaging in neonatal hypoxic-ischemic encephalopathy. Chin J Magn Reson Imaging, 2019, 10(10): 783-786. DOI:10.12015/issn.1674-8034.2019.10.014.

[1]
Wolf RL, Zimmerman RA, Clancy R, et al. Quantitative apparent diffusion coefficient measurements in term neonates for early detection of hypoxic-ischemic brain injury: initial experience. Radiology, 2001, 218(3): 825-833.
[2]
Robertson RL, Ben-Sira L, Barnes PD, et al. MR line-scan diffusion-weighted imaging of term neonates with perinatal brain ischemia. AJNR Am J Neuroradiol, 1999, 20(9): 1658-1670.
[3]
Hayakawa K, Koshino S, Tanda K, et al. Diffusion pseudonormalization and clinical outcome in term neonates with hypoxic-ischemic encephalopathy. Pediatr Radiol, 2018, 48(6): 865-874.
[4]
Alderliesten T, de Vries LS, Benders MJ, et al. MR imaging and outcome of term neonates with perinatal asphyxia: value of diffusion-weighted MR imaging and (1)H MR spectroscopy. Radiology, 2011, 261(1): 235-242.
[5]
Johnson AJ, Lee BC, Lin W. Echoplanar diffusion-weighted imaging in neonates and infants with suspected hypoxic-ischemic injury: correlation with patient outcome. AJR Am J Roentgenol, 1999, 172(1): 219-226.
[6]
Karaarslan E, Arslan A. Diffusion weighted MR imaging in non-infarct lesions of the brain. Eur J Radiol, 2008, 65(3): 402-406.
[7]
Lee YK, Penn A, Patel M, et al. Hypothermia-treated neonates with hypoxic-ischemic encephalopathy: Optimal timing of quantitative ADC measurement to predict disease severity. Neuroradiol J, 2017, 30(1): 28-35.
[8]
Arca-Díaz G, Re TJ, Drottar M, et al. Can cerebellar and brainstem apparent diffusion coefficient (ADC) values predict neuromotor outcome in term neonates with hypoxic-ischemic encephalopathy (HIE) treated with hypothermia?. PLoS One, 2017, 12(7): 17-23.
[9]
Bednarek N, Mathur A, Inder T, et al. Impact of therapeutic hypothermia on MRI diffusion changes in neonatal encephalopathy. Neurology, 2012, 78(18): 420-427.
[10]
Collins LM, Adriaanse LJ, Theratile SD, et al. Class-IIa histone deacetylase inhibition promotes the growth of neural processes and protects them against neurotoxic insult. Mol Neurobiol, 2015, 51(3): 1432-1442.
[11]
Butcher PR, Wijnberg-Williams BJ, Hegemann N, et al. Maternal rigidity in infancy and level of intelligence at school age in children born preterm. Child Psychiatry Hum Dev, 2004, 34(3): 203-217.
[12]
Tusor N, Wusthoff C, Smee N, et al. Prediction of neurodevelopmental outcome after hypoxic-ischemic encephalopathy treated with hypothermia by diffusion tensor imaging analyzed using tract-based spatial statistics. Pediatr Res, 2012, 72(1): 63-69.
[13]
Ward P, Counsell S, Allsop J, et al. Reduced fractional anisotropy on diffusion tensor magnetic resonance imaging after hypoxic-ischemic encephalopathy. Pediatrics, 2006, 117(4): 619-630.
[14]
王玉亮，初建平，磁共振扩散峰度成像(DKI)临床研究进展．影像诊断与介入放射学, 2015, 24(4): 340-345.
[15]
张家慧，郎宁，袁慧书．磁共振扩散峰度成像的临床研究进展．磁共振成像, 2018, 9(4): 316-320.
[16]
Beaulieu C. The basis of anisotropic water diffusion in the nervous system- a technical review. NMR Biomed, 2002, 15(7-8): 435-455.
[17]
Cheung JS, Wang E, Lo EH, et al. Stratification of heterogeneous diffusion MRI ischemic lesion with kurtosis imaging: evaluation of mean diffusion and kurtosis MRI mismatch in an animal model of transient focal ischemia. Stroke, 2012, 43(8): 2252-2254.
[18]
Riddle A, Maire J, Gong X, et al. Differential susceptibility to axonopathy in necrotic and non-necrotic perinatal white matter injury. Stroke, 2012, 43(1): 178-184.
[19]
Gao J, Li X, Li Y, et al. Differentiating T2 hyperintensity in neonatal white matter by two-compartment model of diffusional kurtosis imaging. Sci Rep, 2016, 6(9): 244-247.
[20]
Jensen JH, Falangola MF, Hu C, et al. Preliminary observations of increased diffusional kurtosis in human brain following recent cerebral infarction. NMR Biomed, 2011, 24(5): 452-457.
[21]
陈芳，杨永贵，郭岗．磁共振扩散峰度成像预测急性脑梗死预后的初步研究．磁共振成像, 2018, 9(2): 127-132.
[22]
Leslie-Mazwi TM, Hirsch JA, Falcone GJ, et al. Endovascular stroke treatment outcomes after patient selection based on magnetic resonance imaging and clinical criteria. JAMA Neurol, 2016, 73(1): 43-49.
[23]
Nicoli F, Lefur Y, Denis B, et al. Metabolic counterpart of decreased apparent diffusion coefficient during hyperacute ischemic stroke: a brain proton magnetic resonance spectroscopic imaging study. Stroke, 2003, 34(7): 82-87.
[24]
Nicoli F, Lefur Y, Denis B, et al. How affected is oxygen metabolism in DWI lesions?: A combined acute stroke PET-MR study. Neurology, 2006, 67(5): 824-829.
[25]
Yin J, Sun H, Wang Z, et al. Diffusion kurtosis imaging of acute infarction: Comparison with routine diffusion and follow-up MR imaging. Radiology, 2018, 287(2): 651-657.

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