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Clinical Article
Application of magnetic resonance HASTE and TRUE-FISP sequences in diagnosis of fetal cleft lip and palate
ZHOU Qing  ZHANG He  YIN Xuan  LIU Xuefen  WANG Xuezhen  ZHANG Guofu 

Cite this article as: Zhou Q, Zhang H, Yin X, et al. Application of magnetic resonance HASTE and TRUE-FISP sequences in diagnosis of fetal cleft lip and palate. Chin J Magn Reson Imaging, 2019, 10(11): 817-820. DOI:10.12015/issn.1674-8034.2019.11.004.


[Abstract] Objective: The purpose of this study was to evaluate the value of MRI HASTE and TRUEFISP sequences in diagnosis of cleft lip and cleft palate respectively.Materials and Methods: Half-Fourier single-shot turbo spin echo (HASTE) and true fast imaging with steadystate precession (TRUE-FISP) scanning of 20 pregnant women with cleft lip and palate deformity were analyzed. All images were reviewed by two obstetric MRI diagnosis doctors with 10-year experience. The presence of cleft lip and palate and image quality were scored.Results: Postpartum follow-up results of 20 fetuses showed that 7 were normal fetuses, 3 had cleft lip, 9 had cleft lip and palate, 5 cases occurred on the right side and 4 cases on the left side. The degree of cleft palate was not clear, and 1 had cleft lip and cleft palate. For cleft lip, the diagnostic accuracy of reader 1 in HASTE and TRUE-FISP sequences was 100% and 95% respectively, and that of reader 2 was 95% and 95% respectively. For cleft palate, the diagnostic accuracy of reader 1 in HASTE and TRUE-FISP sequences was 85% and 90% respectively, and that of reader 2 was 85% and 100% respectively. Scanning failure planes: 6 key layers of HASTE sequence were missing. Twelve key scan layers were missing in TRUE-FISP sequence.Conclusions: Coupled with appropriate protocols, MRI scans could evaluate fetal cleft lip and palate with higher accuracy.
[Keywords] cleft lip;cleft palate;fetus;magnetic resonance imaging

ZHOU Qing Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

ZHANG He * Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

YIN Xuan Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

LIU Xuefen Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

WANG Xuezhen Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

ZHANG Guofu * Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200011, China

*Correspondence to: Zhang H, E-mail: dr.zhanghe@yahoo.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by Shanghai Natural Science Foundation No. 19ZR1407200
Received  2019-07-24
DOI: 10.12015/issn.1674-8034.2019.11.004
Cite this article as: Zhou Q, Zhang H, Yin X, et al. Application of magnetic resonance HASTE and TRUE-FISP sequences in diagnosis of fetal cleft lip and palate. Chin J Magn Reson Imaging, 2019, 10(11): 817-820. DOI:10.12015/issn.1674-8034.2019.11.004.

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