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• Clinical Article •
Longitudinal study of somatosensory conduction fiber structure after decompression in patients with cervical spondylotic myelopathy
WU Kaifu  HE Laichang  TAN Yongming 

Cite this article as: Wu KF, He LC, Tan YM, et al. Longitudinal study of somatosensory conduction fiber structure after decompression in patients with cervical spondylotic myelopathy. Chin J Magn Reson Imaging, 2019, 10(11): 830-834. DOI:10.12015/issn.1674-8034.2019.11.007.


[Abstract] Objective: Diffusion tensor imaging (DTI) technique was used to observe the changes of apparent diffusion coefficient (ADC), anisotropy fraction (FA) and mean diffusion coefficient (MD) of somatosensory conduction fibers before and after decompression in patients with cervical spondylotic myelopathy (CSM), and to explore the basis of structural changes in sensory disorders and postoperative neurological recovery in patients with CSM.Materials and Methods: Twenty-seven patients with preoperative CSM and healthy volunteers matched with age and gender received MRI scans (DTI data). Twenty-seven patients with CSM underwent the same scan 6 months after surgery, bilateral thalamocortical tracts and spinothalamic tracts (thalamic-middle brain) as a region of interest, independent or paired sample t-test for three sets of ADC, MD and FA values, analysis of changes in FA, MD and ADC values of the conduction beam between groups to reveal the effect of myelin compression and decompression on the sensory conduction fibers at the distal end of the injury.Results: Compared with the healthy control group, the FA values of the thalamocortical tract and the spinothalamic tract were decreased (P<0.05), and the ADC and MD values of the thalamocortical tract and spinothalamic tract were increased (P<0.05). After 6 months, the value of FA in the thalamocortical of patients with CSM was lower than that of the preCSM group and the control group (P<0.05). The FA value of the spinothalamic tract was higher than that of the preCSM group and the control group (P<0.05).Conclusions: DTI data can quantitatively reflect the degree of secondary injury, which has guiding significance for clinical treatment. CSM can cause secondary and retrograde damage to the thalamocortical tract and spinothalamic tract. The decompression of thalamocortical nerve tracts after decompression is not obvious, but the spinothalamic nerve tracts are remodeled.
[Keywords] cervical spondylotic myelopathy；magnetic resonance imaging；thalamocortical tract；spinothalamic tract

WU Kaifu Department of medical imaging, The First Affiliated Hospital of NanChang University, Nanchang, 330006, China

HE Laichang Department of medical imaging, The First Affiliated Hospital of NanChang University, Nanchang, 330006, China

TAN Yongming * Department of medical imaging, The First Affiliated Hospital of NanChang University, Nanchang, 330006, China

*Correspondence to: Tan YM, E-mail: 627871378@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the National Natural Science Found No. 81460329 Jiangxi Natural Science Foundation No. 20181BAB205063
Received  2019-05-10
DOI: 10.12015/issn.1674-8034.2019.11.007
Cite this article as: Wu KF, He LC, Tan YM, et al. Longitudinal study of somatosensory conduction fiber structure after decompression in patients with cervical spondylotic myelopathy. Chin J Magn Reson Imaging, 2019, 10(11): 830-834. DOI:10.12015/issn.1674-8034.2019.11.007.

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