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• Clinical Article •
The value of mono-exponential, bi-exponentialandstretched, exponential models in identifying brucellosis spondylitis and spinal tuberculos
WU Hui  GAO Yang  LIU Aishi  ZHAO Pengfei  WU Xiaopeng  NIU Guangming 

Cite this article as: Wu H, Gao Y, Liu AS, et al. The value of mono-exponential, bi-exponentialandstretched, exponential models in identifying brucellosis spondylitis and spinal tuberculos. Chin J Magn Reson Imaging, 2019, 10(11): 835-839. DOI:10.12015/issn.1674-8034.2019.11.008.


[Abstract] Objective: To compare the value of various parameters obtained from monoexponential, biexponential, andstretched exponential diffusion-weighted imaging (DWI) models in identification ofbrucellosis spondylitis and spinal tuberculosis.Materials and Methods: Retrospective analysis of our hospital from December 2016 to December 2018 of 34 cases of brucellar spondylitis patients with biochemical detection (SAT 1∶100++ or RBPT++), 31 cases of spinal tuberculosis confirmed by tuberculosis culture and surgical pathology, all patients underwent routine MRI examination and multi-DWI scan. ADC, D, D*, f and DDC, values were measured in BSD group and STB group. comparison between groups using independent sample t test or Wilcoxon test, ROC to differentiate the diagnostic efficacy, Correlation test between variables using Pearson test.Results: ADC, D, D* , f, DDC, a were higher in the BSD group than in the STB group, in addition to f all have statistical significance. ADC, D, DDC, D*, a all have higher differential diagnostic performance, the AUC is 0.87, 0.85, 0.76, 0.71, 0.71, respectively, the thresholds are: 0.000889, 0.000664, 0.00106, 0.00309, 0.81. The correlations of ADC, D and DDC in BSD group and STB group were better, the correlation between ADC and DDC was the strongest in BSD and STB groups, the correlation coefficients were 0.81 and 0.89 respectively.Conclusions: ADC calculated from mono-exponential model and D, D* calculated from bi-exponential model and DDC, a calculated from stretched exponential model all have high performance in identifying brucellosis spondylitis and spinal tuberculos, bi-exponential model provides perfusion information and stretched exponential model provides diffusion heterogeneity information. However, the diagnostic performance of the biexponential model and the stretched exponential model is not higher than the traditional monoexponential model, so DWI is still recommended in clinical practice.
[Keywords] spondylitis；brucella；diffusion magnetic resonance imaging

WU Hui Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

GAO Yang Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

LIU Aishi Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

ZHAO Pengfei Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

WU Xiaopeng Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

NIU Guangming * Department of Radiology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, China

*Correspondence to: Niu GM, E-mail: cjr.niuguangming@vip.163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This paper is supported by the Natural Science Foundation of Inner Mongolia Autonomous Region No. 2017MS (LH) 0837
Received  2019-07-07
DOI: 10.12015/issn.1674-8034.2019.11.008
Cite this article as: Wu H, Gao Y, Liu AS, et al. The value of mono-exponential, bi-exponentialandstretched, exponential models in identifying brucellosis spondylitis and spinal tuberculos. Chin J Magn Reson Imaging, 2019, 10(11): 835-839. DOI:10.12015/issn.1674-8034.2019.11.008.

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