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• Clinical Article •
The relationship between plaque characteristics of intracranial artery stenosis and ischemic stroke
WU Jingjing  JIA Lin  WANG Yunling  HAN Bingyan  JIA Wenxiao 

Cite this article as: Wu JJ, Jia L, Wang YL, et al. The relationship between plaque characteristics of intracranial artery stenosis and ischemic stroke. Chin J Magn Reson Imaging, 2019, 10(12): 881-884. DOI:10.12015/issn.1674-8034.2019.12.001.


[Abstract] Objective: To investigate the relationship between plaque characteristics of patients with intracranial atherosclerotic stenosis and ischemic stroke.Materials and Methods: The plaques of 44 patients with intracranial atherosclerotic stenosis examined by high resolution magnetic resonance imaging (HR-MRI) were retrospectively analyzed. According to 3D-TOF MRA images to analyze the degree of stenosis, the patients were divided into mild stenosis group, moderate stenosis group and severe stenosis group according to the degree of stenosis. According to whether the plaques caused ischemic stroke and the time of ischemic stroke from HR-MRI examination, the plaques were divided into acute/subacute phase responsible plaque group, chronic phase responsible plaque group, and non-responsible plaque group.The risk factors of atherosclerosis and plaque characteristics (stenosis degree and plaque enhancement degree) were compared among the three group.Results: Among 44 patients, 29 were responsible plaques in acute/subacute phase, 20 were responsible plaques in chronic phase and 17 were non-responsible plaques. There were significant differences in the degree of lumen stenosis and plaque enhancement between the acute/subacute responsible plaque group, the chronic responsible plaque group and the non-responsible plaque group (P<0.05). However, there were no statistically significant risk factors for atherosclerosis in the three groups.Conclusions: The degree of plaque enhancement and the degree of stenosis in patients with intracranial atherosclerotic stenosis are correlated with the occurrence of ischemic stroke. The plaques that are obviously strengthened and severely stenosis of the lumen are less stable and more prone to occur ischemic stroke.
[Keywords] magnetic resonance imaging；stroke；atherosclerosis；plaque；stenosis

WU Jingjing The Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830028, China

JIA Lin The Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830028, China

WANG Yunling The Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830028, China

HAN Bingyan The Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830028, China

JIA Wenxiao * The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

*Correspondence to: Jia WX, E-mail: jwxxj@sina.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of National Natural Science Foundation of China No. 81860301
Received  2019-04-21
DOI: 10.12015/issn.1674-8034.2019.12.001
Cite this article as: Wu JJ, Jia L, Wang YL, et al. The relationship between plaque characteristics of intracranial artery stenosis and ischemic stroke. Chin J Magn Reson Imaging, 2019, 10(12): 881-884. DOI:10.12015/issn.1674-8034.2019.12.001.

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